Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | ECE1 | P42892 | 8/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13360514 | 0.85 | KDM4E (0.44) | KDM4EL3MBTL1ALDH1A1TDP1MAPK1 | |
| SCHEMBL7225742 | 0.77 | KDM4E (1.00) | KDM4EL3MBTL1ECE1ALOX15ALDH1A1 | |
| SCHEMBL13363185 | 0.77 | KDM4E (0.68) | KDM4EL3MBTL1ECE1ALOX15ALDH1A1 | |
| SCHEMBL7234015 | 0.77 | KDM4E (0.68) | KDM4EL3MBTL1ECE1ALOX15ALDH1A1 | |
| SCHEMBL29375401 | 0.75 | KDM4E (0.66) | KDM4EL3MBTL1ECE1ALOX15ALDH1A1 | |
| SCHEMBL1759891 | 0.75 | KDM4E (0.66) | KDM4EL3MBTL1ECE1ALOX15ALDH1A1 | |
| SCHEMBL8825399 | 0.75 | KDM4E (0.66) | KDM4EL3MBTL1ECE1ALOX15ALDH1A1 | |
| SCHEMBL7226508 | 0.75 | KDM4E (0.66) | KDM4EL3MBTL1ECE1ALOX15ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7235077 | 0.75 | KDM4E (0.66) | KDM4EL3MBTL1ECE1ALOX15ALDH1A1 | |
| SCHEMBL13348981 | 0.74 | KDM4E (0.38) | KDM4EL3MBTL1ALDH1A1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113442-A1 | TRIAZOLOPYRIDINES AS PHOSPHODIESTERASE INHIBITORS FOR TREATMENT OF DERMAL DISEASES | FELDING JAKOB | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113442-A1 | TRIAZOLOPYRIDINES AS PHOSPHODIESTERASE INHIBITORS FOR TREATMENT OF DERMAL DISEASES | PDE5A, PDE3A, PDE3B | KDM4E 1090/4885L3MBTL1 3852/4885ECE1 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.