Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | ECE1 | P42892 | 7/20 | 0.50 |
| ▸ | CTSA | P10619 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | KMO | O15229 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1759891 | 1.00 | KDM4E (0.66) | KDM4EL3MBTL1ECE1CTSAALOX15 | |
| Hydrochloric Acid SCHEMBL7225758 | 0.98 | KDM4E (0.64) | KDM4EL3MBTL1ECE1CTSAALOX15 | |
| SCHEMBL73021 | 0.85 | KDM4E (0.47) | KDM4EL3MBTL1ECE1CTSAALDH1A1 | |
| SCHEMBL7236303 | 0.84 | CTSA (0.48) | KDM4EL3MBTL1CTSAALDH1A1MAPT | |
| SCHEMBL7225755 | 0.82 | KDM4E (0.45) | KDM4EL3MBTL1ECE1CTSAALDH1A1 | |
| SCHEMBL16741093 | 0.82 | KDM4E (0.49) | KDM4EL3MBTL1ECE1CTSAKMO | |
| SCHEMBL2816376 | 0.81 | KMO (0.49) | KDM4EL3MBTL1CTSAALOX15KMO | |
| SCHEMBL7234015 | 0.79 | KDM4E (0.68) | KDM4EL3MBTL1ECE1ALOX15ALDH1A1 | |
| SCHEMBL13363185 | 0.79 | KDM4E (0.68) | KDM4EL3MBTL1ECE1ALOX15ALDH1A1 | |
| SCHEMBL7225742 | 0.79 | KDM4E (1.00) | KDM4EL3MBTL1ECE1ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946301-A1 | REMODILINS FOR AIRWAY REMODELING AND ORGAN FIBROSIS | The University of Chicago (US) | 2022-02-09 | — | — | EP | disclosed |