Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | ECE1 | P42892 | 7/20 | 0.50 |
| ▸ | CTSA | P10619 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10200957 | 0.85 | KDM4E (0.47) | KDM4EL3MBTL1ECE1CTSAALDH1A1 | |
| SCHEMBL29750003 | 0.85 | KDM4E (0.47) | KDM4EL3MBTL1ECE1CTSAALDH1A1 | |
| SCHEMBL7107317 | 0.84 | CTSA (0.47) | KDM4EL3MBTL1CTSAALDH1A1 | |
| SCHEMBL7234015 | 0.83 | KDM4E (0.68) | KDM4EL3MBTL1ECE1ALOX15ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7235077 | 0.81 | KDM4E (0.66) | KDM4EL3MBTL1ECE1ALOX15ALDH1A1 | |
| SCHEMBL15595925 | 0.81 | HPGDS (0.46) | KDM4EL3MBTL1ECE1CTSAALDH1A1 | |
| SCHEMBL10112914 | 0.80 | CTSA (0.53) | KDM4EL3MBTL1CTSAALDH1A1CA1 | |
| SCHEMBL16533522 | 0.80 | CTSA (0.44) | KDM4EL3MBTL1ECE1CTSAALOX15 | |
| SCHEMBL16517813 | 0.80 | KDM4E (0.42) | KDM4EL3MBTL1ECE1CTSAALDH1A1 | |
| SCHEMBL13363185 | 0.79 | KDM4E (0.68) | KDM4EL3MBTL1ECE1ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250376457-A1 | DICHLOROPHENOL HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM INC (US) | 2025-12-11 | — | — | US | disclosed |
| US-20240208929-A1 | HYDROXYPYRIDINE HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. | 2024-06-27 | — | — | US | disclosed |
| US-20240208929-A1 | HYDROXYPYRIDINE HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. | 2024-06-27 | — | — | US | disclosed |
| US-20240150314-A1 | DICHLOROPHENOL HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. | 2024-05-09 | — | — | US | disclosed |
| US-11827619-B2 | Dichlorophenol HSD17B13 inhibitors and uses thereof | INIPHARM, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827619-B2 | Dichlorophenol HSD17B13 inhibitors and uses thereof | INIPHARM, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827619-B2 | Dichlorophenol HSD17B13 inhibitors and uses thereof | INIPHARM, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| EP-4244210-A1 | DICHLOROPHENOL HSD17B13 INHIBITORS AND USES THEREOF | Inipharm, Inc. (US) | 2023-09-20 | — | — | EP | disclosed |
| US-20230278981-A1 | DICHLOROPHENOL HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. | 2023-09-07 | — | — | US | disclosed |
| US-20230278981-A1 | DICHLOROPHENOL HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. | 2023-09-07 | — | — | US | disclosed |
| US-20120252809-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2012-10-04 | — | — | US | disclosed |
| WO-2012101197-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2012-08-02 | — | — | WO | disclosed |
| US-20120015926-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | TONG LING (US) | 2012-01-19 | — | — | US | disclosed |
| US-20120010181-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | MERCK SHARP & DOHME CORP. | 2012-01-12 | — | — | US | disclosed |
| US-20120010181-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | MERCK SHARP & DOHME CORP. | 2012-01-12 | — | — | US | disclosed |
| WO-2010054279-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION (US) | 2010-05-14 | — | — | WO | disclosed |
| US-6610853-B1 | N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide | KUREHA KAGAKU KOGYO K.K. (JP) | 2003-08-26 | — | — | US | disclosed |
| EP-1069112-A1 | N-(PHENYLSULFONYL) PICOLINAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6159901-A | 6-phenoxy picolinic acid alkylidene hydrazide derivative, process for producing the same and herbicide using the same | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-1020444-A1 | 6-PHENOXYPICOLINIC ACID, ALKYLIDENEHYDRAZIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250376457-A1 | DICHLOROPHENOL HSD17B13 INHIBITORS AND USES THEREOF | HSD17B1, HSD17B3, HSD17B13 | KDM4E 3481/4885L3MBTL1 2950/4885ECE1 1677/4885 |
| US-20120252809-A1 | SUBSTITUTED 3-HETEROAROYLAMINO-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | CTSL, CTSF, CTSV | KDM4E 3014/4885L3MBTL1 1340/4885ECE1 80/4885 |
| US-20240208929-A1 | HYDROXYPYRIDINE HSD17B13 INHIBITORS AND USES THEREOF | HSD17B3, HSD17B1, HSD17B13 | KDM4E 2653/4885L3MBTL1 4167/4885ECE1 1103/4885 |
| US-20120015926-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | TNF, ADAMTS1, ADAMTS7 | KDM4E 4592/4885L3MBTL1 4865/4885ECE1 203/4885 |
| US-20120010181-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | TNF, ADAMTS1, ADAMTS7 | KDM4E 4576/4885L3MBTL1 4820/4885ECE1 216/4885 |
| US-20230278981-A1 | DICHLOROPHENOL HSD17B13 INHIBITORS AND USES THEREOF | HSD17B1, HSD17B3, HSD17B13 | KDM4E 3481/4885L3MBTL1 2950/4885ECE1 1677/4885 |
| US-20240150314-A1 | DICHLOROPHENOL HSD17B13 INHIBITORS AND USES THEREOF | HSD17B1, HSD17B3, HSD17B13 | KDM4E 3481/4885L3MBTL1 2950/4885ECE1 1677/4885 |
| US-11827619-B2 | Dichlorophenol HSD17B13 inhibitors and uses thereof | HSD17B1, HSD17B3, HSD17B13 | KDM4E 3481/4885L3MBTL1 2950/4885ECE1 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.