Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 4/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.53 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.53 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | PDE5A | O76074 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13360711 | 0.90 | HSP90AA1 (0.70) | HSP90AA1ESR1ABCG2ESR2AKR1B10 | |
| SCHEMBL24305496 | 0.83 | MAPT (0.60) | HSP90AA1ESR1ABCG2ESR2AKR1B10 | |
| SCHEMBL13360710 | 0.81 | PTPN1 (0.74) | HSP90AA1ESR1ABCG2ESR2AKR1B10 | |
| SCHEMBL571650 | 0.78 | HSP90AA1 (0.77) | HSP90AA1ESR1ABCG2ESR2AKR1B10 | |
| SCHEMBL12961707 | 0.77 | ESR1 (0.84) | ESR1ABCG2ESR2AKR1B10AKR1B1 | |
| Water SCHEMBL1999608 | 0.77 | HSP90AA1 (0.76) | HSP90AA1ESR1ABCG2ESR2AKR1B10 | |
| SCHEMBL27013629 | 0.74 | HSP90AA1 (1.00) | HSP90AA1ESR1ABCG2ESR2AKR1B10 | |
| SCHEMBL30266617 | 0.74 | HSP90AA1 (1.00) | HSP90AA1ESR1ABCG2ESR2AKR1B10 | |
| SCHEMBL16259003 | 0.72 | ODC1 (0.54) | HSP90AA1PDE5APTPN1MAPTKMT2A | |
| Sophoraflavanone B SCHEMBL14304885 | 0.70 | ESR1 (1.00) | ESR1ABCG2ESR2AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723088-B2 | DNA sequences involved in prenylflavonoid biosynthesis in hops and their use in modifying prenylflavonoid production in plants | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2010-05-25 | — | — | US | disclosed |
| US-20090222946-A1 | DNA SEQUENCES INVOLVED IN PRENYLFLAVONOID BIOSYNTHESIS IN HOPS AND THEIR USE IN MODIFYING PRENYLFLAVONOID PRODUCTION IN PLANTS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2009-09-03 | — | — | US | disclosed |