Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 3/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18906968 | 0.87 | ODC1 (0.70) | ODC1PTPN1CYP3A4MEN1MAPT | |
| SCHEMBL24305496 | 0.83 | MAPT (0.60) | PTPN1MEN1MAPTKMT2APOLB | |
| SCHEMBL18906966 | 0.79 | ODC1 (0.62) | ODC1PTPN1CYP3A4MEN1MAPT | |
| Lupinifolinol SCHEMBL6668491 | 0.77 | PTPN1 (0.50) | ODC1PTPN1CYP3A4MEN1MAPT | |
| Lupinifolin SCHEMBL6207285 | 0.74 | MAPT (0.68) | ODC1PTPN1MEN1MAPTKMT2A | |
| SCHEMBL13360711 | 0.74 | HSP90AA1 (0.70) | PTPN1CYP3A4MEN1MAPTKMT2A | |
| SCHEMBL31345893 | 0.74 | CYP3A4 (0.56) | ODC1PTPN1CYP3A4MEN1MAPT | |
| SCHEMBL13360710 | 0.74 | PTPN1 (0.74) | PTPN1MEN1MAPTKMT2APOLB | |
| SCHEMBL13360712 | 0.72 | HSP90AA1 (0.58) | PTPN1CYP3A4MEN1MAPTKMT2A | |
| Eriosemaone A SCHEMBL31753876 | 0.72 | IDO1 (0.73) | ODC1PTPN1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9956199-B2 | Chromane-like cyclic prenylflavonoids for the medical intervention in neurological disorders | Aigner, Ludwig (DE) | 2018-05-01 | — | — | US | disclosed |
| US-9956199-B2 | Chromane-like cyclic prenylflavonoids for the medical intervention in neurological disorders | Aigner, Ludwig (DE) | 2018-05-01 | — | — | US | disclosed |
| US-20170128411-A1 | CHROMANE-LIKE CYCLIC PRENYLFLAVONOIDS FOR THE MEDICAL INTERVENTION IN NEUROLOGICAL DISORDERS | Aigner, Ludwig (AT) | 2017-05-11 | — | — | US | disclosed |
| US-20170128411-A1 | CHROMANE-LIKE CYCLIC PRENYLFLAVONOIDS FOR THE MEDICAL INTERVENTION IN NEUROLOGICAL DISORDERS | Aigner, Ludwig (AT) | 2017-05-11 | — | — | US | disclosed |
| US-9527860-B2 | Chromane-like cyclic prenylflavonoids for the medical intervention in neurological disorders | Aigner, Ludwig (AT) | 2016-12-27 | — | — | US | disclosed |
| US-9527860-B2 | Chromane-like cyclic prenylflavonoids for the medical intervention in neurological disorders | Aigner, Ludwig (AT) | 2016-12-27 | — | — | US | disclosed |
| US-20140349919-A1 | CHROMANE-LIKE CYCLIC PRENYLFLAVONOIDS FOR THE MEDICAL INTERVENTION IN NEUROLOGICAL DISORDERS | COUILLARD-DESPRES, Sébastien (AT) | 2014-11-27 | — | — | US | disclosed |
| US-20140349919-A1 | CHROMANE-LIKE CYCLIC PRENYLFLAVONOIDS FOR THE MEDICAL INTERVENTION IN NEUROLOGICAL DISORDERS | COUILLARD-DESPRES, Sébastien (AT) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170128411-A1 | CHROMANE-LIKE CYCLIC PRENYLFLAVONOIDS FOR THE MEDICAL INTERVENTION IN NEUROLOGICAL DISORDERS | BDNF, MAP2, DCX | ODC1 4119/4885PTPN1 3650/4885CYP3A4 4360/4885 |
| US-20140349919-A1 | CHROMANE-LIKE CYCLIC PRENYLFLAVONOIDS FOR THE MEDICAL INTERVENTION IN NEUROLOGICAL DISORDERS | BDNF, MAP2, DCX | ODC1 4119/4885PTPN1 3650/4885CYP3A4 4360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.