Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.74 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.61 |
| ▸ | ESR1 | P03372 | 3/20 | 0.61 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523853 | 0.87 | PTPN1 (0.81) | PTPN1CACNA1HESR1CACNA1GMAPT | |
| SCHEMBL5614193 | 0.85 | PTPN1 (1.00) | PTPN1CACNA1HESR1CACNA1GMAPT | |
| SCHEMBL29375421 | 0.85 | PTPN1 (1.00) | PTPN1CACNA1HESR1CACNA1GMAPT | |
| SCHEMBL13360711 | 0.83 | HSP90AA1 (0.70) | PTPN1CACNA1HESR1CACNA1GMAPT | |
| SCHEMBL24305496 | 0.82 | MAPT (0.60) | PTPN1CACNA1HESR1CACNA1GMAPT | |
| SCHEMBL13360712 | 0.81 | HSP90AA1 (0.58) | PTPN1CACNA1HESR1CACNA1GMAPT | |
| SCHEMBL30288230 | 0.80 | PTPN1 (0.81) | PTPN1GABRA1GABRB2HSP90AA1ACHE | |
| SCHEMBL22922168 | 0.79 | GABRA1 (0.66) | PTPN1CACNA1HESR1CACNA1GMAPT | |
| SCHEMBL30634928 | 0.79 | GABRA1 (0.66) | PTPN1CACNA1HESR1CACNA1GMAPT | |
| SCHEMBL27013458 | 0.79 | GABRA1 (0.66) | PTPN1CACNA1HESR1CACNA1GMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723088-B2 | DNA sequences involved in prenylflavonoid biosynthesis in hops and their use in modifying prenylflavonoid production in plants | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2010-05-25 | — | — | US | disclosed |
| US-20090222946-A1 | DNA SEQUENCES INVOLVED IN PRENYLFLAVONOID BIOSYNTHESIS IN HOPS AND THEIR USE IN MODIFYING PRENYLFLAVONOID PRODUCTION IN PLANTS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2009-09-03 | — | — | US | disclosed |