Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 16/20 | 0.60 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3355166 | 0.87 | ROCK2 (0.49) | ROCK2ROCK1 | |
| SCHEMBL3356239 | 0.84 | ROCK2 (0.56) | ROCK2ROCK1 | |
| SCHEMBL3384750 | 0.84 | ROCK2 (0.63) | ROCK2 | |
| SCHEMBL13362628 | 0.82 | ROCK2 (0.64) | ROCK2 | |
| SCHEMBL3389345 | 0.80 | ROCK2 (0.45) | ROCK2 | |
| SCHEMBL3359796 | 0.77 | ROCK2 (0.51) | ROCK2ROCK1 | |
| SCHEMBL3354682 | 0.76 | ROCK2 (0.53) | ROCK2NISCHROCK1 | |
| SCHEMBL13457106 | 0.75 | ROCK2 (1.00) | ROCK2 | |
| SCHEMBL13362938 | 0.74 | ROCK2 (0.37) | ROCK2NISCH | |
| SCHEMBL3359299 | 0.74 | ROCK2 (0.55) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056758-A1 | QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-05-20 | — | — | WO | disclosed |