Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | CTSA | P10619 | 1/20 | 0.37 |
| ▸ | MAN2A1 | Q16706 | 1/20 | 0.36 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3347110 | 0.87 | TRPV3 (0.40) | TRPV3KDM1AMAOAMAOBCD274 | |
| SCHEMBL3347106 | 0.87 | TRPV3 (0.40) | TRPV3KDM1AMAOAMAOBCD274 | |
| SCHEMBL14067123 | 0.73 | KDM1A (0.49) | TRPV3KDM1AMAOAMAOBADORA2A | |
| SCHEMBL22445577 | 0.71 | TDP1 (0.58) | GPR88LMNA | |
| SCHEMBL12493466 | 0.71 | TDP1 (0.58) | GPR88LMNA | |
| SCHEMBL18114399 | 0.71 | CASR (0.60) | — | |
| SCHEMBL3350666 | 0.71 | KDM1A (0.38) | TRPV3KDM1AMAOAMAOBADORA2A | |
| SCHEMBL8485251 | 0.71 | KDM1A (0.52) | TRPV3KDM1AMAOAMAOBCD274 | |
| SCHEMBL8827525 | 0.71 | KDM1A (0.50) | TRPV3KDM1AMAOAMAOBADORA2A | |
| SCHEMBL27088833 | 0.71 | VSIR (0.54) | TRPV3KDM1AMAOAMAOBCD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | disclosed |