Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133664 | 1.00 | CYP2C19 (0.60) | CYP2C19RELATSHRNR1H2NR1H3 | |
| SCHEMBL4403046 | 0.98 | CYP2C19 (0.62) | CYP2C19RELATSHRNR1H2NR1H3 | |
| SCHEMBL14308069 | 0.89 | RELA (0.67) | CYP2C19RELATSHRKMT2AALDH1A1 | |
| SCHEMBL12763843 | 0.89 | TSHR (0.70) | CYP2C19RELATSHRNR1H2NR1H3 | |
| SCHEMBL4402948 | 0.87 | TSHR (0.72) | CYP2C19RELATSHRNR1H2NR1H3 | |
| SCHEMBL2960872 | 0.85 | CYP2C19 (0.78) | CYP2C19TSHRNR1H2NR1H3CNR2 | |
| SCHEMBL13778827 | 0.84 | TSHR (0.62) | CYP2C19RELATSHRNR1H2NR1H3 | |
| SCHEMBL1165356 | 0.82 | CYP2C19 (0.58) | CYP2C19TSHRNR1H2NR1H3CNR2 | |
| SCHEMBL9718472 | 0.82 | CYP2C19 (0.58) | CYP2C19TSHRNR1H2NR1H3CNR2 | |
| SCHEMBL10863384 | 0.81 | CHAT (0.49) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596754-A | Electroconductive support, photosensitive layer comprising azo pigment charge generating layer, charge transport layer, alkali soluble resin | RICOH COMPANY, LTD. (JP) | 1986-06-24 | — | — | US | claimed |
| US-9235146-B2 | Photoconductor | RICOH COMPANY, LTD. (JP) | 2016-01-12 | — | — | US | disclosed |
| US-9040215-B2 | Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2015-05-26 | — | — | US | disclosed |
| US-9005856-B2 | Hydroxygallium porphyrazine derivative mixture and electrophotographic photoconductor | RICOH COMPANY, LTD. (JP) | 2015-04-14 | — | — | US | disclosed |
| US-20150079509-A1 | PHOTOCONDUCTOR | RICOH COMPANY, LTD. (JP) | 2015-03-19 | — | — | US | disclosed |
| US-8889324-B2 | Image bearing member, image forming method, image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2014-11-18 | — | — | US | disclosed |
| US-8809543-B2 | Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge for electrophotographic image forming apparatus | RICOH COMPANY, LTD. (JP) | 2014-08-19 | — | — | US | disclosed |
| US-8586270-B2 | Electrophotographic photoconductor, electrophotographic method, and electrophotographic apparatus | RICOH COMPANY, LTD. (JP) | 2013-11-19 | — | — | US | disclosed |
| US-20130202994-A1 | AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2013-08-08 | — | — | US | disclosed |
| US-8304153-B2 | Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, electrophotographic process cartridge | RICOH COMPANY, LTD. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-4716220-A | CHARGE CARRIER GENERATING MATERIALS | RICOH CO., LTD. (JP) | 1987-12-29 | — | — | US | disclosed |
| US-4708921-A | Photosensitive material containing disazo compound for use in electrophotography | RICOH CO., LTD. (JP) | 1987-11-24 | — | — | US | disclosed |
| US-4702979-A | ELECTROCONDUCTIVE CATHODE LAYER, PHOTOCONDUCTIVE LAYER OF CHARGE-GENERATING ORGANIC PIGMENT, ANODIC ION REACTION AT INTERFACE WHEN IRRADIATED | RICOH CO., LTD. (JP) | 1987-10-27 | — | — | US | disclosed |
| US-4672149-A | PHOTOACTIVE LAYER CONTAINING A DISAZO PIGMENT; SOLAR CELLS; EFFICIENCY | RICOH CO., LTD. (JP) | 1987-06-09 | — | — | US | disclosed |
| US-4663442-A | ELECTROGRAPHY, PHOTOSENSITIVITY | RICOH CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |
| US-4619878-A | Tetrazonium salt compound, disazo compound, method for preparing the same, and photosensitive material containing said disazo compound for use in electrophotography | RICOH CO., LTD. (JP) | 1986-10-28 | — | — | US | disclosed |
| US-4596754-A | Electroconductive support, photosensitive layer comprising azo pigment charge generating layer, charge transport layer, alkali soluble resin | RICOH COMPANY, LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| US-4582771-A | Disazo compound, method for preparing the same, and electrophotographic element containing the same for use in electrophotography | RICOH CO., LTD. (JP) | 1986-04-15 | — | — | US | disclosed |
| US-4565759-A | PHOTOCONDUCTIVE LAYER ON ELECTROCONDUCTIVE SUPPORT | RICOH CO., LTD. (JP) | 1986-01-21 | — | — | US | disclosed |
| US-4540643-A | Tetrazonium salt compounds, novel disazo compounds, method for the production thereof and disazo compound-containing electrophotographic elements | RICOH CO., LTD. (JP) | 1985-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130202994-A1 | AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | ARL1, ATXN2L, AHR | CYP2C19 849/4885RELA 3386/4885TSHR 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.