SCHEMBL9718472

SCHEMBL9718472

C=Cc1ccc(N(Cc2ccccc2)Cc2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.58
TSHR P16473 4/20 0.50
ALDH1A1 P00352 6/20 0.48
NR1H2 P55055 1/20 0.47
NR1H3 Q13133 1/20 0.47
CNR2 P34972 2/20 0.46
LMNA P02545 5/20 0.46
KDM4E B2RXH2 3/20 0.46
MAPT P10636 3/20 0.46
KMT2A Q03164 3/20 0.46
HPGD P15428 2/20 0.46
MAPK1 P28482 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
MITF O75030 1/20 0.46
RAD52 P43351 1/20 0.46
GAA P10253 2/20 0.44
ALOX12 P18054 1/20 0.44
HTT P42858 1/20 0.44
NR3C1 P04150 1/20 0.43
CYP2D6 P10635 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19066615 0.92 TSHR (0.50) CYP2C19TSHRALDH1A1NR1H2NR1H3
SCHEMBL6389774 0.90 ALDH1A1 (0.48) CYP2C19TSHRALDH1A1NR1H2NR1H3
SCHEMBL17191291 0.90 TSHR (0.68) CYP2C19TSHRALDH1A1NR1H2NR1H3
SCHEMBL1677966 0.90 CYP2C19 (0.47) CYP2C19TSHRALDH1A1NR1H2NR1H3
SCHEMBL19066618 0.85 TSHR (0.45) CYP2C19TSHRALDH1A1NR1H2NR1H3
SCHEMBL4403046 0.84 CYP2C19 (0.62) CYP2C19TSHRALDH1A1NR1H2NR1H3
SCHEMBL2960872 0.83 CYP2C19 (0.78) CYP2C19TSHRALDH1A1NR1H2NR1H3
SCHEMBL3357025 0.83 TSHR (0.46) CYP2C19TSHRALDH1A1CNR2LMNA
SCHEMBL133664 0.82 CYP2C19 (0.60) CYP2C19TSHRALDH1A1NR1H2NR1H3
SCHEMBL133663 0.82 CYP2C19 (0.60) CYP2C19TSHRALDH1A1NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838188-B2 Electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2010-11-23 US disclosed
US-7838188-B2 Electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2010-11-23 US disclosed
US-20070231720-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-10-04 US disclosed
US-20070231720-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-10-04 US disclosed
US-5080989-A Polycarbonate, solvent resistance EASTMAN KODAK COMPANY (US) 1992-01-14 US disclosed
US-4322487-A Composite electrically photosensitive particles for electrophoretic migration imaging process EASTMAN KODAK COMPANY (US) 1982-03-30 US disclosed
EP-0024169-A2 Electrically photosensitive particles for electrophoretic migration imaging processes, dispersions of these particles, and processes using such dispersions EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-02-25 EP disclosed