Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 4/20 | 0.37 |
| ▸ | POR | P16435 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 4/20 | 0.35 |
| ▸ | SUZ12 | Q15022 | 4/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 4/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18020194 | 0.70 | CES1 (0.46) | NQO1PORMEN1KMT2AMAPT | |
| SCHEMBL5940262 | 0.68 | NQO1 (0.68) | NQO1PORMEN1KMT2AMAPT | |
| SCHEMBL29353628 | 0.67 | CES1 (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL88188 | 0.67 | CES1 (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL31741221 | 0.65 | CES1 (0.50) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28310427 | 0.65 | CES1 (0.50) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL10556518 | 0.65 | MAOA (0.53) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL28195032 | 0.65 | CES1 (0.50) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| Toluene SCHEMBL8373044 | 0.65 | LMNA (0.52) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL2987590 | 0.63 | CDC25B (0.48) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056041-A2 | PHARMACEUTICAL COMPOSITION FOR TREATING AND PREVENTING HEART DISEASES CAUSED BY ISCHEMIA OR ISCHEMIC REPERFUSION | 주식회사 머젠스 (KR) | 2010-05-20 | — | — | WO | disclosed |