SCHEMBL13367388

SCHEMBL13367388

Cc1cc(C)cc(N(C)c2ccccc2C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 0.39
ACHE P22303 2/20 0.36
TSHR P16473 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
MAPK13 O15264 1/20 0.35
MAPK12 P53778 1/20 0.35
MAPK11 Q15759 1/20 0.35
MAPK14 Q16539 1/20 0.35
TRPM8 Q7Z2W7 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B1 P14061 2/20 0.33
HSD17B2 P37059 2/20 0.33
GPBAR1 Q8TDU6 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
RXRA P19793 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13367468 0.84 CSF1R (0.45) ACHETSHRSIGMAR1MAPK13MAPK12
SCHEMBL13367414 0.81 TSHR (0.46) ACHETSHRSIGMAR1MAPK13MAPK12
SCHEMBL20210134 0.81 CYP1A2 (0.39) ACHETSHRSIGMAR1SLC6A2SLC6A4
SCHEMBL20384981 0.80 TSHR (0.41) ACHETSHRSIGMAR1TRPM8SLC6A2
SCHEMBL2198610 0.80 TSHR (0.41) ACHETSHRSIGMAR1TRPM8SLC6A2
SCHEMBL2620728 0.79 ACHE (0.50) ACHETSHRSIGMAR1TRPM8SLC6A2
SCHEMBL22336610 0.79 ALDH1A1 (0.37) TSPOACHETSHRTP53MAPT
SCHEMBL20210151 0.78 MAPK13 (0.40) ACHETSHRSIGMAR1MAPK13MAPK12
SCHEMBL8652577 0.78 CYP3A4 (0.46) ACHETSHRSIGMAR1MAPK13MAPK12
SCHEMBL10296013 0.77 ACHE (0.40) TSPOACHETSHRSIGMAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 TSPO 1826/4885ACHE 2234/4885TSHR 3278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.