Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12132125 | 0.83 | ALDH1A1 (0.39) | F2RKMT2AALDH1A1TDO2MAPT | |
| SCHEMBL1336684 | 0.81 | PRKDC (0.41) | F2RKMT2ACYP19A1CYP11B1CYP11B2 | |
| SCHEMBL1337699 | 0.81 | ALDH1A1 (0.37) | F2RKMT2AS1PR4ALDH1A1TDO2 | |
| SCHEMBL1337889 | 0.78 | MEN1 (0.49) | KMT2AALDH1A1MAPTMEN1PRKDC | |
| SCHEMBL28449950 | 0.78 | PDE10A (0.51) | KMT2AALDH1A1MAPTMEN1ERN1 | |
| SCHEMBL1337919 | 0.77 | MEN1 (0.44) | KMT2ACYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL29957260 | 0.76 | S1PR4 (0.53) | KMT2AS1PR4ALDH1A1MAPTMEN1 | |
| SCHEMBL1337920 | 0.75 | F2R (0.39) | F2RKMT2AALDH1A1TDO2MAPT | |
| SCHEMBL4898660 | 0.72 | ALDH1A1 (0.50) | KMT2AS1PR4ALDH1A1MAPTTSHR | |
| SCHEMBL1337297 | 0.72 | PDE3B (0.46) | CYP19A1ALDH1A1ERN1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275643-A1 | AROYLQUINOLINE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-11-10 | — | — | US | disclosed |
| US-20110275643-A1 | AROYLQUINOLINE COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275643-A1 | AROYLQUINOLINE COMPOUNDS | TUBA1C, TUBB1, TUBB3 | F2R 3541/4885KMT2A 1581/4885CYP19A1 987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.