Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | TACR2 | P21452 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210233 | 1.00 | KCNH2 (0.46) | KCNH2TDP1L3MBTL1ESR1ADRA2A | |
| SCHEMBL5209751 | 1.00 | KCNH2 (0.46) | KCNH2TDP1L3MBTL1ESR1ADRA2A | |
| SCHEMBL5207581 | 1.00 | KCNH2 (0.46) | KCNH2TDP1L3MBTL1ESR1ADRA2A | |
| SCHEMBL4865067 | 1.00 | KCNH2 (0.46) | KCNH2TDP1L3MBTL1ESR1ADRA2A | |
| SCHEMBL533252 | 1.00 | KCNH2 (0.46) | KCNH2TDP1L3MBTL1ESR1ADRA2A | |
| SCHEMBL828059 | 1.00 | KCNH2 (0.46) | KCNH2TDP1L3MBTL1ESR1ADRA2A | |
| SCHEMBL10602889 | 1.00 | KCNH2 (0.46) | KCNH2TDP1L3MBTL1ESR1ADRA2A | |
| SCHEMBL263493 | 1.00 | KCNH2 (0.46) | KCNH2TDP1L3MBTL1ESR1ADRA2A | |
| SCHEMBL20774553 | 1.00 | KCNH2 (0.46) | KCNH2TDP1L3MBTL1ESR1ADRA2A | |
| SCHEMBL4208084 | 1.00 | KCNH2 (0.46) | KCNH2TDP1L3MBTL1ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217913-A2 | PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND | HUA MEDICINE (SHANGHAI) LTD. (CN) | 2024-07-04 | — | — | US | claimed |
| US-20230312455-A1 | PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND | HUA MEDICINE (SHANGHAI) LTD. (CN) | 2023-10-05 | — | — | US | claimed |
| CN-114085146-B | Preparation of substituted acrylate compounds | 华领医药技术（上海）有限公司 | 2023-09-01 | — | — | CN | claimed |
| EP-4206175-A1 | PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND | Hua Medicine (Shanghai) Ltd. (CN) | 2023-07-05 | — | — | EP | claimed |
| CN-114085146-A | Preparation of substituted acrylate compounds | 华领医药技术（上海）有限公司 | 2022-02-25 | — | — | CN | claimed |
| US-7429548-B2 | Soluble late transition metal catalysts for olefin oligomerizations III | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-09-30 | — | — | US | claimed |
| EP-1620447-B1 | SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS III | EXXONMOBIL CHEM PATENTS INC (US) | 2007-08-08 | — | — | EP | claimed |
| US-7161018-B2 | Soluble late transition metal catalysts for olefin oligomerizations II | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-01-09 | — | — | US | claimed |
| EP-1513854-B1 | SOLUBLE LATE TRANSITION METAL CATALYSTS FOR OLEFIN OLIGOMERIZATIONS | EXXONMOBIL CHEM PATENTS INC (US) | 2006-11-29 | — | — | EP | claimed |
| US-20060036049-A1 | Soluble late transition metal catalysts for olefin oligomerizations III | ZHAO BAIYI | 2006-02-16 | — | — | US | claimed |
| US-20240217913-A2 | PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND | HUA MEDICINE (SHANGHAI) LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
| CN-118244579-A | Colored curable composition, color filter and display device | 住友化学株式会社 | 2024-06-25 | — | — | CN | disclosed |
| CN-118244578-A | Colored curable composition, color filter and display device | 住友化学株式会社 | 2024-06-25 | — | — | CN | disclosed |
| CN-117916327-A | Colored curable composition | 住友化学株式会社 | 2024-04-19 | — | — | CN | disclosed |
| CN-117916326-A | Colored curable composition | 住友化学株式会社 | 2024-04-19 | — | — | CN | disclosed |
| US-5446180-A | Compounds containing 1-aza-3-oxa-4-silacyclohex-1-enyl groups, and tautomers of said compounds | DOW CORNING ASIA LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0661290-A1 | Compounds containing 1-aza-3-oxa-4-silacyclohex-1-enyl groups, and tautomers of said compounds | DOW CORNING ASIA, Ltd. (JP) | 1995-07-05 | — | — | EP | disclosed |
| EP-0451948-B1 | Heterocyclicacetonitriles and their fungicidal use | ROHM & HAAS (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5001091-A | Readily moldable or castable ceramic powders | NORTON COMPANY (US) | 1991-03-19 | — | — | US | disclosed |
| US-4221918-A | CATALYTIC HYDROGENATION OF CARBOXYLIC ANHYDRIDES | CHEVRON RESEARCH COMPANY (US) | 1980-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060036049-A1 | Soluble late transition metal catalysts for olefin oligomerizations III | COMT, CD69, SPR | KCNH2 2822/4885TDP1 3174/4885L3MBTL1 1451/4885 |
| US-20230312455-A1 | PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND | ACR, ADCYAP1R1, GNPAT | KCNH2 1859/4885TDP1 2871/4885L3MBTL1 4773/4885 |
| US-20240217913-A2 | PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND | ACR, ADCYAP1R1, GNPAT | KCNH2 1859/4885TDP1 2871/4885L3MBTL1 4773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.