⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3997999 | 1.00 | — | — | |
| SCHEMBL1336752 | 1.00 | — | — | |
| SCHEMBL3326931 | 0.87 | — | — | |
| SCHEMBL433732 | 0.85 | — | — | |
| SCHEMBL1828378 | 0.85 | — | — | |
| SCHEMBL433731 | 0.85 | — | — | |
| SCHEMBL1828379 | 0.85 | — | — | |
| SCHEMBL18689744 | 0.85 | GLO1 (0.38) | — | |
| SCHEMBL18689745 | 0.85 | GLO1 (0.38) | — | |
| SCHEMBL965901 | 0.82 | EP300 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957124-A | 3- (trifluoromethyl) -pyrazole-4-carboxylic ester derivative and preparation method and application thereof | 浙江工业大学 | 2022-08-30 | — | — | CN | claimed |
| EP-3442974-B1 | PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| CN-114957124-A | 3- (trifluoromethyl) -pyrazole-4-carboxylic ester derivative and preparation method and application thereof | 浙江工业大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-109071545-B | Novel pyrazolopyrimidine derivatives | 拜耳动物保健有限责任公司 | 2021-08-03 | — | — | CN | disclosed |
| US-11001590-B2 | Pyrazolopyrimidine derivatives | BAYER ANIMAL HEALTH GMBH (DE) | 2021-05-11 | — | — | US | disclosed |
| EP-3807266-A1 | PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS | Janssen Pharmaceutica N.V. (BE) | 2021-04-21 | — | — | EP | disclosed |
| US-10934301-B2 | Pyrazolopyrimidine derivatives | BAYER ANIMAL HEALTH GMBH (DE) | 2021-03-02 | — | — | US | disclosed |
| US-20200407364-A1 | FUSED BICYCLIC COMPOUNDS | AKARNA THERAPEUTICS LTD (GB) | 2020-12-31 | — | — | US | disclosed |
| EP-3468964-B1 | MODULATORS OF SOCE, COMPOSITIONS, AND USES THEREOF | UNIV DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO (IT) | 2020-12-30 | — | — | EP | disclosed |
| US-20200299299-A1 | NEW PYRAZOLOPYRIMIDINE DERIVATIVES | BAYER ANIMAL HEALTH GMBH (DE) | 2020-09-24 | — | — | US | disclosed |
| US-20090221663-A1 | PYRAZOLE DERIVATIVES AS 11-BETA-HSD1 INHIBITORS | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | US | disclosed |
| WO-2008099145-A1 | PYRAZOLE DERIVATIVES AS 11-BETA-HSD1 INHIBITORS | ASTRAZENECA AB (SE) | 2008-08-21 | — | — | WO | disclosed |
| US-20080154045-A1 | Process for Producing 1-Substituted-3-Fluoroalkylpyrazole-4-Carboxylate | SAGAMI CHEMICAL RESEARCKH CENTER (JP) | 2008-06-26 | — | — | US | disclosed |
| US-7345180-B2 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2008-03-18 | — | — | US | disclosed |
| EP-1854788-A1 | METHOD FOR PRODUCING 1-SUBSTITUTED-3-FLUOROALKYL PYRAZOLE-4-CARBOXYLATE | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2007-11-14 | — | — | EP | disclosed |
| US-20060229286-A1 | Compound inhibiting dipeptidyl peptidase IV | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1595866-A1 | COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV | Sanwa Kagaku Kenkyusho Co., Ltd. (JP) | 2005-11-16 | — | — | EP | disclosed |
| EP-0151866-B1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | ELI LILLY AND COMPANY (US) | 1990-07-25 | — | — | EP | disclosed |
| US-4620865-A | Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides | ELI LILLY AND COMPANY (US) | 1986-11-04 | — | — | US | disclosed |
| EP-0151866-A2 | Herbicidal pyrazole-(thio)-carboxamides | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |