Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15478776 | 1.00 | GAA (0.52) | GAACA2CA1CA9CA12 | |
| SCHEMBL30896660 | 0.91 | GAA (0.56) | GAACA2CA1CA9CA12 | |
| SCHEMBL1149214 | 0.81 | GAA (0.56) | GAACA2CA1CA9CA12 | |
| SCHEMBL178444 | 0.81 | GAA (0.56) | GAACA2CA1CA9CA12 | |
| SCHEMBL27694463 | 0.79 | GAA (0.54) | GAACA2CA1CA9CA12 | |
| SCHEMBL16623120 | 0.79 | HTR6 (0.46) | CA2CA1CA9CA12CA7 | |
| SCHEMBL9385444 | 0.79 | GAA (0.54) | GAACA2CA1CA9CA12 | |
| SCHEMBL21818 | 0.79 | GAA (0.54) | GAACA2CA1CA9CA12 | |
| SCHEMBL25678915 | 0.78 | GAA (0.48) | GAACA2CA1CA9CA12 | |
| SCHEMBL26343853 | 0.78 | GAA (0.59) | GAACA2CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100112683-A2 | Thermal Cycler for Automatic Performance of the Polymerase Chain Reaction with Close Temperature Control | APPLIED BIOSYSTEMS, LLC (US) | 2010-05-06 | — | — | US | disclosed |