SCHEMBL178444

SCHEMBL178444

Cc1ccc(S(=O)(=O)C(C)C)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.56
CA2 P00918 5/20 0.52
CA1 P00915 4/20 0.52
CA12 O43570 3/20 0.52
CA9 Q16790 3/20 0.52
CA3 P07451 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
ALDH1A1 P00352 6/20 0.50
TLR9 Q9NR96 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.48
MMP1 P03956 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
MMP13 P45452 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10060475 0.89 ALDH1A1 (0.40) GAACA2CA1CA12CA9
Biphenyl SCHEMBL11056125 0.88 CA12 (0.46) GAACA2CA1CA12CA9
SCHEMBL30896660 0.85 GAA (0.56) GAACA2CA1CA12CA9
SCHEMBL1149214 0.85 GAA (0.56) GAACA2CA1CA12CA9
SCHEMBL26343877 0.84 GAA (0.50) GAACA2CA1CA12CA9
SCHEMBL14850014 0.84 GAA (0.50) GAACA2CA1CA12CA9
SCHEMBL9385444 0.83 GAA (0.54) GAACA2CA1CA12CA9
SCHEMBL10060466 0.82 CA12 (0.46) CA2CA1CA12CA9SMN1; SMN2
SCHEMBL26343853 0.82 GAA (0.59) GAACA2CA1CA12CA9
SCHEMBL5346463 0.81 GAA (0.52) GAACA2CA1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 416 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233823-A Synthesis method of 2-fluoro-1, 3-propane sultone 张家港市国泰华荣化工新材料有限公司 2020-06-05 CN claimed
CN-119585651-A Composition for forming wavelength conversion film 日产化学株式会社 2025-03-07 CN disclosed
WO-2024214539-A1 COMPOSITION FOR FORMING WAVELENGTH CONVERSION FILM, AND COMPOUND 日産化学株式会社 2024-10-17 WO disclosed
US-20240217913-A2 PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND HUA MEDICINE (SHANGHAI) LTD. (CN) 2024-07-04 US disclosed
EP-3790886-B1 KRAS G12C INHIBITORS FOR THE TREATMENT OF CANCER AMGEN INC (US) 2024-06-26 EP disclosed
US-11912736-B2 Diaryl trehalose compounds and uses thereof THE UNIVERSITY OF MONTANA (US) 2024-02-27 US disclosed
WO-2024029475-A1 WAVELENGTH CONVERSION FILM FORMING COMPOSITION 日産化学株式会社 2024-02-08 WO disclosed
EP-4306520-A1 THIOPHENE COMPOUND AND APPLICATION THEREOF Medshine Discovery Inc. (CN) 2024-01-17 EP disclosed
CN-107615168-B Radiation-sensitive composition 日产化学工业株式会社 2023-12-19 CN disclosed
US-20230364274-A1 IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING FIBROBLAST-ACTIVATION PROTEIN-ALPHA (FAP-ALPHA) THE JOHNS HOPKINS UNIVERSTY 2023-11-16 US disclosed
WO-1991007384-A1 PROCESS FOR THE PRODUCTION OF ALKYL-(3-CHLOROPHENYL) SULPHONES HOECHST AKTIENGESELLSCHAFT (DE) 1991-05-30 WO disclosed
US-4556732-A INTERMEDIATE IN THE PRODUCTION OF ESTERS HAVING INSECTICIDAL ACTIVITY ROUSSEL UCLAF (FR) 1985-12-03 US disclosed
US-4501704-A Aromatic sulfonyl alkanoates and alkylnitriles ROUSSEL UCLAF (FR) 1985-02-26 US disclosed
US-4500720-A Tetrahydrofuran-2-ones ROUSSEL UCLAF (FR) 1985-02-19 US disclosed
US-4443617-A Process for the preparation of derivatives of 6,6-dimethyl-4-hydroxy-3-oxabicyclo-[3,1,0]-hexan-2-one ROUSSEL UCLAF (FR) 1984-04-17 US disclosed
US-4420433-A REACTION WITH SILICON TETRACHLORIDE OR TITANIUM TETRACHLORIDE BAYER AKTIENGESELLSCHAFT (DE) 1983-12-13 US disclosed
US-4401601-A Novel process for the preparation of tetra-substituted cyclopropane compounds ROUSSEL UCLAF (FR) 1983-08-30 US disclosed
US-4390724-A Process for the preparation of 3-formyl-4-R2 R3 -but-3-ene-1-oic acids ROUSSEL UCLAF (FR) 1983-06-28 US disclosed
EP-0071065-A1 Process for the preparation of fluorine-substituted carboxylic-acid chlorides and aldehydes BAYER AG (DE) 1983-02-09 EP disclosed
EP-0007672-A1 Isocyanoalkenes, process and useful intermediates for their preparation, pharmaceutical and fungicidal preparations containing those isocyanoalkenes and the use of the fungicidal preparations in agriculture GIST-BROCADES N.V. (NL) 1980-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240217913-A2 PREPARATION OF SUBSTITUTED ACRYLATE COMPOUND ACR, ADCYAP1R1, GNPAT GAA 373/4885CA2 4487/4885CA1 3640/4885
US-20230364274-A1 IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING FIBROBLAST-ACTIVATION PROTEIN-ALPHA (FAP-ALPHA) FAP, FIBP, FGFR1 GAA 35/4885CA2 3448/4885CA1 3895/4885
US-11912736-B2 Diaryl trehalose compounds and uses thereof TREH, STT3B, DDOST GAA 39/4885CA2 1958/4885CA1 1399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.