Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22555764 | 0.86 | TSHR (0.62) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL10754352 | 0.86 | TSHR (0.67) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL1843156 | 0.85 | TSHR (0.58) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL1402713 | 0.84 | TSHR (0.59) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL27521802 | 0.84 | SMN1; SMN2 (0.61) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL9716465 | 0.83 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL10585663 | 0.82 | TSHR (0.65) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL28262735 | 0.81 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL28633009 | 0.80 | TSHR (0.53) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL8669169 | 0.80 | ALDH1A1 (0.72) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100117027-A1 | Polymerizable liquid crystal composition | CHISSO CORPORATION | 2010-05-13 | — | — | US | disclosed |