Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CALML3 | P27482 | 6/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10152104 | 0.88 | MAOA (0.48) | CYP3A4CYP2D6CALML3MAOAF10 | |
| SCHEMBL13367839 | 0.86 | MAOA (0.40) | CYP3A4CYP2D6CALML3MAOAF10 | |
| SCHEMBL13357948 | 0.85 | CALML3 (0.36) | CYP3A4CALML3MAOAF10GRM2 | |
| SCHEMBL13358120 | 0.82 | MAOA (0.42) | CALML3MAOAF10GRM2 | |
| SCHEMBL10152106 | 0.81 | MAOB (0.40) | CYP3A4CYP2D6CALML3MAOAF10 | |
| SCHEMBL11983842 | 0.79 | MAOA (0.50) | CALML3MAOAF10 | |
| SCHEMBL13981014 | 0.78 | CYP3A4 (0.39) | CYP3A4CYP2D6CALML3MAOAF10 | |
| SCHEMBL10151840 | 0.77 | MAOA (0.62) | CALML3MAOAF10 | |
| SCHEMBL13368091 | 0.75 | MAOB (0.45) | CALML3MAOAF10 | |
| SCHEMBL10151842 | 0.74 | MAOB (0.51) | CALML3MAOAF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2181993-A1 | Antimicrobial oxazolidinone derivatives | Research Foundation Itsuu Laboratory (JP) | 2010-05-05 | — | — | EP | disclosed |