SCHEMBL1337100

SCHEMBL1337100

CCN(C)c1ccccc1C#N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
ALDH1A1 P00352 3/20 0.42
HTT P42858 1/20 0.42
GAA P10253 3/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
CYP19A1 P11511 1/20 0.38
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
CYP11B1 P15538 1/20 0.35
CYP11B2 P19099 1/20 0.35
KMT2A Q03164 1/20 0.35
HDAC6 Q9UBN7 2/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28367614 0.82 TSHR (0.42) TSHRALDH1A1HTTGAAKDM4E
SCHEMBL2560142 0.82 TSHR (0.45) TSHRALDH1A1HTTGAAKDM4E
SCHEMBL27957024 0.81 TSHR (0.41) TSHRALDH1A1HTTGAAKDM4E
SCHEMBL5167168 0.80 ALDH1A1 (0.31) TSHRALDH1A1HTTGAAMAPT
SCHEMBL5950092 0.79 TSHR (0.39) TSHRALDH1A1HTTGAAKDM4E
SCHEMBL28483720 0.79 TSHR (0.39) TSHRALDH1A1HTTGAAKDM4E
SCHEMBL148781 0.79 ALDH1A1 (0.55) TSHRALDH1A1HTTGAAKDM4E
SCHEMBL28315215 0.78 TSHR (0.42) TSHRALDH1A1HTTGAAKDM4E
SCHEMBL28029326 0.78 TSHR (0.42) TSHRALDH1A1HTTGAAKDM4E
SCHEMBL31718392 0.78 SIGMAR1 (0.37) TSHRALDH1A1HTTGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009073570-A2 LIGHT- AND DUAL-CURE DENTAL RESINS AND ADHESIVES WITH INCREASED CURE AND COLOR-STABILITY, AND LOW COLOR BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2009-06-11 WO claimed
EP-4518794-A1 RADIATION-CURABLE COMPOSITION FOR USE IN A RAPID PROTOTYPING PROCESS OR A RAPID MANUFACTURING PROCESS Kulzer GmbH (DE) 2025-03-12 EP disclosed
EP-3689290-B1 METHOD FOR PRODUCING A PARTIAL OR TOTAL PROSTHESIS, AND PROSTHESIS OBTAINABLE BY THIS METHOD KULZER & CO GMBH (DE) 2023-11-22 EP disclosed
WO-2023213699-A1 RADIATION-CURABLE COMPOSITION FOR USE IN A RAPID PROTOTYPING PROCESS OR A RAPID MANUFACTURING PROCESS KULZER GMBH (DE) 2023-11-09 WO disclosed
CN-115943053-A Radiation curable compositions for rapid prototyping or rapid manufacturing processes 古莎有限公司 2023-04-07 CN disclosed
EP-4122422-A1 RADIATION-CURABLE COMPOSITION FOR USE IN RAPID PROTOTYPING OR RAPID MANUFACTURING METHODS Kulzer GmbH (DE) 2023-01-25 EP disclosed
EP-4039223-A1 RADIATION-CURABLE COMPOSITION FOR USE IN RAPID PROTOTYPING OR RAPID MANUFACTURING METHODS Kulzer GmbH (DE) 2022-08-10 EP disclosed
EP-3164097-B1 MILL BLANKS BASED ON A POLYMERIZED, FRACTURE-TOUGH PROSTHESIS MATERIAL KULZER & CO GMBH (DE) 2022-05-11 EP disclosed
EP-3481328-B9 MULTI-COLORED MILLING BLANK FOR PROSTHETIC DENTAL FIXTURES WHICH ARE SUPPORTED ON AN IMPLANT, METHOD OF MANUFACTURING AND USE KULZER & CO GMBH (DE) 2021-12-29 EP disclosed
EP-3924186-A1 RADIATION-CURABLE COMPOSITION FOR USE IN RAPID PROTOTYPING OR RAPID MANUFACTURING METHODS Kulzer GmbH (DE) 2021-12-22 EP disclosed
EP-0449399-B1 POLYMERIZABLE DENTAL COMPOSITION IVOCLAR AG (LI) 1993-05-19 EP disclosed
EP-0539811-A2 Chlorhexidine adduct IVOCLAR AG (LI) 1993-05-05 EP disclosed
US-5179186-A Irradiation polymerization of macrodiol, aliphatic polyisocyanate, and unsaturated monoalcohol as chain terminator to form polyurethane BAYER AKTIENGESELLSCHAFT (DE) 1993-01-12 US disclosed
US-5095045-A PLASTICS WHICH CURE IN A SERIES OF STEPS HAVING URETHANE, UREA, SILOXANE AND ACRYLATE GROUPS BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US disclosed
EP-0460478-A2 Light hardenable impression materials BAYER AG (DE) 1991-12-11 EP disclosed
EP-0449399-A2 Polymerizable dental composition IVOCLAR AG (LI) 1991-10-02 EP disclosed
EP-0195224-B1 PROCESS FOR PREPARING ARTIFICIAL TEETH OR TOOTH PARTS AND STORAGE-STABLE DENTAL MATERIAL SUITED THEREFOR Etablissement Dentaire IVOCLAR (LI) 1990-09-26 EP disclosed
EP-0262488-B1 REACTIVE ORGANIC FILLER AND ITS USE Ivoclar AG (LI) 1990-06-06 EP disclosed
EP-0262488-A1 Reactive organic filler and its use Ivoclar AG (LI) 1988-04-06 EP disclosed
EP-0195224-A2 Process for preparing artificial teeth or tooth parts and storage-stable dental material suited therefor Etablissement Dentaire IVOCLAR (LI) 1986-09-24 EP disclosed