Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6866612 | 0.88 | MAOA (0.57) | MAOAMAOBSMN1; SMN2CHRM2HRH3 | |
| SCHEMBL6866606 | 0.88 | MAOA (0.57) | MAOAMAOBSMN1; SMN2CHRM2HRH3 | |
| SCHEMBL18871477 | 0.78 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL15066769 | 0.78 | SMN1; SMN2 (0.53) | MAOAMAOBSMN1; SMN2CHRM2HRH3 | |
| SCHEMBL399162 | 0.77 | SMN1; SMN2 (0.56) | MAOAMAOBSMN1; SMN2CHRM2ALDH1A1 | |
| SCHEMBL14465565 | 0.77 | MAOA (0.53) | MAOAMAOBSMN1; SMN2CHRM2HRH3 | |
| SCHEMBL26780011 | 0.77 | MAOA (0.53) | MAOAMAOBSMN1; SMN2CHRM2HRH3 | |
| SCHEMBL12614725 | 0.77 | MAOA (0.53) | MAOAMAOBSMN1; SMN2CHRM2HRH3 | |
| SCHEMBL825190 | 0.76 | SMN1; SMN2 (0.47) | MAOAMAOBSMN1; SMN2CHRM2ALDH1A1 | |
| SCHEMBL11135849 | 0.76 | ALDH1A1 (0.66) | MAOAMAOBSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |