Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | QPCT | Q16769 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30265449 | 0.91 | QPCT (0.62) | ALDH1A1POLBMAPTTSHRHPGD | |
| SCHEMBL3153245 | 0.80 | POLB (0.62) | ALDH1A1POLBHPGDQPCTMAPK1 | |
| SCHEMBL13373392 | 0.77 | RAB9A (0.61) | ALDH1A1POLBMAPTHPGDNPC1 | |
| SCHEMBL3632497 | 0.77 | QPCT (0.83) | ALDH1A1POLBMAPTHPGDNPC1 | |
| SCHEMBL2355361 | 0.77 | HTT (0.55) | POLBNPC1RAB9ATDP1KMT2A | |
| SCHEMBL13373317 | 0.77 | POLB (0.61) | POLBCYP3A4HTTHSD17B10MAPK1 | |
| SCHEMBL5407291 | 0.76 | MAPT (0.64) | ALDH1A1POLBMAPTTSHRHPGD | |
| SCHEMBL13373394 | 0.76 | CASP6 (0.61) | ALDH1A1POLBMAPTHPGDTP53 | |
| SCHEMBL2351821 | 0.76 | HTT (0.57) | ALDH1A1POLBMAPTHPGDTP53 | |
| SCHEMBL13373328 | 0.76 | POLB (0.63) | ALDH1A1POLBMAPTHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |