Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12388161 | 0.86 | MAPT (0.46) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL13373367 | 0.79 | MAPT (0.40) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL23742733 | 0.79 | MAPT (0.46) | MAPTKDM4EALDH1A1APEX1RECQL | |
| Dimedazol SCHEMBL312977 | 0.77 | MAPT (0.56) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL22433010 | 0.76 | MAPT (0.50) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL3925343 | 0.74 | MAPT (0.48) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL7216263 | 0.74 | MAPT (0.48) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL13373330 | 0.71 | MAPT (0.46) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL3050263 | 0.71 | MAPT (0.48) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL3925348 | 0.71 | MAPT (0.48) | MAPTKDM4EALDH1A1APEX1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |