SCHEMBL1337364

SCHEMBL1337364

C=C(C(N)=O)c1ccc[nH]1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
CYP1A2 P05177 3/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ATM Q13315 1/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP2D6 P10635 2/20 0.38
CYP1B1 Q16678 1/20 0.38
GAA P10253 1/20 0.38
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13656487 0.82 TSHR (0.43) TSHRCYP1A2RAB9ASMN1; SMN2ATM
SCHEMBL797502 0.81 TSHR (0.50) TSHRCYP1A2RAB9ASMN1; SMN2ATM
SCHEMBL8632904 0.80 TSHR (0.42) TSHRCYP1A2RAB9ASMN1; SMN2ATM
SCHEMBL1126578 0.78 TSHR (0.47) TSHRCYP1A2RAB9ASMN1; SMN2ATM
SCHEMBL30350 0.78
SCHEMBL6782595 0.78 TSHR (0.50) TSHRCYP1A2RAB9ASMN1; SMN2ATM
SCHEMBL1608665 0.76 HDAC1 (0.43) TSHRCYP1A2ATMCYP2D6CYP1B1
Hydrochloric Acid SCHEMBL6052939 0.76
Bromide SCHEMBL3617299 0.76
Fluoride SCHEMBL28479463 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3247353-A2 HETEROCYCLIC ITK INHIBITORS FOR TREATING INFLAMMATION AND CANCER Confluence Life Sciences, Inc. (US) 2017-11-29 EP disclosed
WO-2016118951-A2 HETEROCYCLIC ITK INHIBITORS FOR TREATING INFLAMMATION AND CANCER CONFLUENCE LIFE SCIENCES, INC. (US) 2016-07-28 WO disclosed
US-8795858-B2 Magnetic recording medium and method of manufacturing the same FUJIFILM CORPORATION (JP) 2014-08-05 US disclosed
US-8632896-B2 Radiation-curable vinyl chloride copolymer, radiation-curable composition, and magnetic recording medium FUJIFILM CORPORATION (JP) 2014-01-21 US disclosed
US-8617728-B2 Magnetic tape and method of manufacturing the same FUJIFILM CORPORATION (JP) 2013-12-31 US disclosed
US-8603652-B2 Magnetic recording medium FUJIFILM CORPORATION (JP) 2013-12-10 US disclosed
US-20110274947-A1 MAGNETIC RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2011-11-10 US disclosed
US-20110229740-A1 MAGNETIC TAPE AND METHOD OF MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2011-09-22 US disclosed
US-20110229741-A1 MAGNETIC RECORDING MEDIUM AND METHOD OF MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2011-09-22 US disclosed
EP-1905787-B1 Lithographic printing plate precursor using a polymer latex of high acrylonitrile content FUJIFILM CORP (JP) 2011-05-18 EP disclosed
US-20110111258-A1 RADIATION-CURABLE VINYL CHLORIDE COPOLYMER, RADIATION-CURABLE COMPOSITION, AND MAGNETIC RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2011-05-12 US disclosed
US-7745076-B2 Dye-containing curable composition, color filter, and producing process thereof FUJIFILM CORPORATION (JP) 2010-06-29 US disclosed
US-20080281058-A1 PROCESS FOR PRODUCING ACRYLONITRILE-CONTAINING POLYMER LATEX FUJIFILM CORPORATION (JP) 2008-11-13 US disclosed
US-20080176151-A1 DYE-CONTAINING CURABLE COMPOSITION, COLOR FILTER, AND PRODUCING PROCESS THEREOF FUJIFILM CORPORATION 2008-07-24 US disclosed
EP-1935910-A2 Process for producing acrylonitrile-containing polymer latex FUJIFILM Corporation (JP) 2008-06-25 EP disclosed
US-20080096132-A1 mixing a polymerizable monomer in which acrylonitrile accounts for 70% by weight or more of a total of the polymerizable monomer, water and an alkali metal persulfate polymerization initiator to conduct emulsion polymerization; distilling off unpolymerized monomers; chemical resistance film, gas barrier FUJIFILM CORPORATION 2008-04-24 US disclosed
US-7358033-B2 Dye-containing curable composition, color filter, and producing process thereof FUJIFILM CORPORATION (JP) 2008-04-15 US disclosed
EP-1905787-A2 Polymer latex of high acrylonitrile content, film, pattern forming material and lithographic printing plate precursor using the same, and method for production of polymer latex FUJIFILM Corporation (JP) 2008-04-02 EP disclosed
US-20030232259-A1 Dye-containing curable composition, color filter, and producing process thereof FUJI PHOTO FILM CO., LTD. 2003-12-18 US disclosed