Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13656487 | 0.84 | TSHR (0.43) | TSHRCYP2D6CYP1A2RAB9ASMN1; SMN2 | |
| SCHEMBL1337364 | 0.81 | TSHR (0.44) | TSHRCYP2D6CYP1A2GAARAB9A | |
| SCHEMBL10475040 | 0.80 | TSHR (0.42) | TSHRCYP2D6CYP1A2GAARAB9A | |
| SCHEMBL1608665 | 0.78 | HDAC1 (0.43) | TSHRCYP2D6CYP1A2ATM | |
| Formaldehyde SCHEMBL27470039 | 0.77 | TSHR (0.53) | TSHRCYP2D6CYP1A2GAARAB9A | |
| SCHEMBL1127485 | 0.77 | TSHR (0.53) | TSHRCYP2D6CYP1A2GAARAB9A | |
| SCHEMBL28298 | 0.77 | — | — | |
| SCHEMBL10141202 | 0.77 | — | — | |
| SCHEMBL21114388 | 0.77 | TSHR (0.57) | TSHRCYP2D6CYP1A2GAARAB9A | |
| SCHEMBL10141203 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167501-B2 | Methods and apparatus for quantification of nucleic acid amplification by monitoring impedances | AUCKLAND UNISERVICES LIMITED (NZ) | 2019-01-01 | — | — | US | claimed |
| US-20160046977-A1 | Methods and Apparatus for Amplifying Nucleic Acids | AUCKLAND UNISERVICES LIMITED (NZ) | 2016-02-18 | — | — | US | claimed |
| EP-0802782-B1 | PROPHYLACTIC AND THERAPEUTIC TREATMENT OF SKIN SENSITIZATION AND IRRITATION | BRISTOL MYERS SQUIBB CO (US) | 2003-02-05 | — | — | EP | claimed |
| US-5995869-A | Reduction of skin sensitization in electrotransport drug delivery | ALZA CORPORATION (US) | 1999-11-30 | — | — | US | claimed |
| US-5912010-A | ADMINISTERING LOOP DIURETIC ALONE OR WITH MAST CELL DEGRANULATOR OR GLUCOCORTICOSTEROID | E.R. SQUIBB & SONS, INC. (US) | 1999-06-15 | — | — | US | claimed |
| US-5843979-A | Transdermal treatment with mast cell degranulating agents for drug-induced hypersensitivity | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-12-01 | — | — | US | claimed |
| EP-0802782-A4 | PROPHYLACTIC AND THERAPEUTIC TREATMENT OF SKIN SENSITIZATION AND IRRITATION | BRISTOL MYERS SQUIBB CO (US) | 1998-04-01 | — | — | EP | claimed |
| WO-1997047355-A1 | REDUCTION OF SKIN SENSITIZATION IN ELECTROTRANSPORT DRUG DELIVERY | ALZA CORPORATION (US) | 1997-12-18 | — | — | WO | claimed |
| US-5686100-A | Prophylactic and therapeutic treatment of skin sensitization and irritation | E.R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | claimed |
| EP-0802782-A1 | PROPHYLACTIC AND THERAPEUTIC TREATMENT OF SKIN SENSITIZATION AND IRRITATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-10-29 | — | — | EP | claimed |
| WO-1996015771-A1 | PROPHYLACTIC AND THERAPEUTIC TREATMENT OF SKIN SENSITIZATION AND IRRITATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-05-30 | — | — | WO | claimed |
| EP-0612525-A1 | Transdermal treatment with mast cell degranulating agents for drug-induced hypersensitivity | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-08-31 | — | — | EP | claimed |
| CN-108456240-B | Isosteviol derivative and preparation and application thereof | 山东大学 | 2020-05-12 | — | — | CN | disclosed |
| US-10167501-B2 | Methods and apparatus for quantification of nucleic acid amplification by monitoring impedances | AUCKLAND UNISERVICES LIMITED (NZ) | 2019-01-01 | — | — | US | disclosed |
| WO-2016176450-A1 | TAMBJAMINES AND B-RING FUNCTIONALIZED PRODIGININES | PORTLAND STATE UNIVERSITY (US) | 2016-11-03 | — | — | WO | disclosed |
| US-20160046977-A1 | Methods and Apparatus for Amplifying Nucleic Acids | AUCKLAND UNISERVICES LIMITED (NZ) | 2016-02-18 | — | — | US | disclosed |
| WO-1997047355-A1 | REDUCTION OF SKIN SENSITIZATION IN ELECTROTRANSPORT DRUG DELIVERY | ALZA CORPORATION (US) | 1997-12-18 | — | — | WO | disclosed |
| US-5686100-A | Prophylactic and therapeutic treatment of skin sensitization and irritation | E.R. SQUIBB & SONS, INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0273572-B1 | Pyrrole derivatives and their use in agriculture | ZENECA LTD (GB) | 1996-01-24 | — | — | EP | disclosed |
| EP-0612525-A1 | Transdermal treatment with mast cell degranulating agents for drug-induced hypersensitivity | BRISTOL-MYERS SQUIBB COMPANY (US) | 1994-08-31 | — | — | EP | disclosed |