Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 3/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 3/20 | 0.38 |
| ▸ | EP300 | Q09472 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | F12 | P00748 | 3/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951628 | 0.93 | RBP4 (0.39) | RBP4NR1H2C5AR1EP300CREBBP | |
| SCHEMBL5952792 | 0.85 | RBP4 (0.45) | RBP4NR1H2EP300CREBBP | |
| SCHEMBL5070030 | 0.83 | F12 (0.41) | NR1H2C5AR1F12ESR2ADORA1 | |
| SCHEMBL29386147 | 0.80 | RBP4 (0.42) | RBP4NR1H2EP300CREBBPNAMPT | |
| SCHEMBL30074122 | 0.80 | EP300 (0.55) | RBP4C5AR1EP300CREBBP | |
| SCHEMBL5952658 | 0.78 | HDAC1 (0.41) | NAMPTHDAC1 | |
| SCHEMBL25430237 | 0.78 | ADORA1 (0.43) | RBP4NR1H2C5AR1EP300CREBBP | |
| SCHEMBL4792110 | 0.76 | ADORA1 (0.46) | RBP4NR1H2EP300CREBBPESR2 | |
| SCHEMBL14520683 | 0.76 | ESR2 (0.41) | RBP4NR1H2EP300CREBBPESR2 | |
| SCHEMBL4795587 | 0.76 | NPC1 (0.48) | RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |