Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22664218 | 0.98 | MEN1 (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL24193577 | 0.98 | MEN1 (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL25876080 | 0.98 | MEN1 (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL25475907 | 0.98 | MEN1 (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL13374400 | 0.94 | MEN1 (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL23518488 | 0.89 | MEN1 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL20198781 | 0.85 | SIGMAR1 (0.50) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL22664217 | 0.83 | FFAR1 (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL21015239 | 0.83 | MEN1 (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2CASP2 | |
| SCHEMBL20121987 | 0.83 | CASP2 (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158152-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | MEDSHINE DISCOVERY INC. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20230158152-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | MEDSHINE DISCOVERY INC. (CN) | 2023-05-25 | — | — | US | disclosed |
| US-20220175722-A1 | DEGRADERS OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 (FGFR2) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-06-09 | — | — | US | disclosed |
| US-10301324-B2 | Ataxia telengiectasia and rad3-related (ATR) inhibitors and methods of their use | Atrin Pharmaceuticals LLC (US) | 2019-05-28 | — | — | US | disclosed |
| US-9950064-B2 | Branched and linear chimeric compounds, polynucleotides, uses and methods for preparation thereof | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2018-04-24 | — | — | US | disclosed |
| US-20170291911-A1 | Ataxia Telengiectasia And RAD3-Related (ATR) Inhibitors And Methods Of Their Use | Atrin Pharmaceuticals LLC | 2017-10-12 | — | — | US | disclosed |
| US-20170291911-A1 | Ataxia Telengiectasia And RAD3-Related (ATR) Inhibitors And Methods Of Their Use | Atrin Pharmaceuticals LLC | 2017-10-12 | — | — | US | disclosed |
| US-20160213774-A1 | BRANCHED AND LINEAR CHIMERIC COMPOUNDS, POLYNUCLEOTIDES, USES AND METHODS FOR PREPARATION THEREOF | DYNAVAX TECHNOLOGIES CORPORATION | 2016-07-28 | — | — | US | disclosed |
| US-20130203659-A1 | GLP-1 COMPOUNDS | MIRANDA LESLIE P (US) | 2013-08-08 | — | — | US | disclosed |
| US-8288339-B2 | GLP-1 compounds | AMGEN INC. (US) | 2012-10-16 | — | — | US | disclosed |
| US-20100048468-A1 | GLP-1 COMPOUNDS | AMGEN INC. (US) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160213774-A1 | BRANCHED AND LINEAR CHIMERIC COMPOUNDS, POLYNUCLEOTIDES, USES AND METHODS FOR PREPARATION THEREOF | PAICS, PBK, PHAX | MEN1 3016/4885KMT2A 2816/4885ALDH1A1 4448/4885 |
| US-20220175722-A1 | DEGRADERS OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 (FGFR2) | FGFR2, FGF2, FGFR1 | MEN1 3032/4885KMT2A 618/4885ALDH1A1 2103/4885 |
| US-20230158152-A1 | PROTEOLYSIS REGULATOR AND METHOD FOR USING SAME | PSMA6, PSMC1, PSMA1 | MEN1 3479/4885KMT2A 1544/4885ALDH1A1 4341/4885 |
| US-10301324-B2 | Ataxia telengiectasia and rad3-related (ATR) inhibitors and methods of their use | ATR, CHEK2, CHEK1 | MEN1 1307/4885KMT2A 1652/4885ALDH1A1 4748/4885 |
| US-20100048468-A1 | GLP-1 COMPOUNDS | GLP1R, IAPP, GIPR | MEN1 169/4885KMT2A 3312/4885ALDH1A1 3928/4885 |
| US-20130203659-A1 | GLP-1 COMPOUNDS | GLP1R, IAPP, GIPR | MEN1 169/4885KMT2A 3312/4885ALDH1A1 3928/4885 |
| US-20170291911-A1 | Ataxia Telengiectasia And RAD3-Related (ATR) Inhibitors And Methods Of Their Use | ATR, CHEK2, CHEK1 | MEN1 1307/4885KMT2A 1652/4885ALDH1A1 4748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.