SCHEMBL13374609

SCHEMBL13374609

c1ccc(Nc2ccc(-c3ccc(N(c4ccc(-c5ccccc5)cc4)c4ccc(-c5ccccc5)cc4)c4ccccc34)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
HSD17B10 Q99714 4/20 0.39
ALDH1A1 P00352 4/20 0.39
ALOX15 P16050 3/20 0.39
TSHR P16473 3/20 0.39
MAPK1 P28482 3/20 0.39
ALOX12 P18054 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
PTGS1 P23219 1/20 0.39
SLC6A2 P23975 1/20 0.39
PTGS2 P35354 1/20 0.39
HTR2B P41595 1/20 0.39
KDM1A O60341 7/20 0.39
EPHX2 P34913 1/20 0.37
CYP3A4 P08684 3/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2C19 P33261 2/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13903639 0.89 RXRA (0.46) RXRARXRBHSD17B10ALDH1A1MAPK1
SCHEMBL13903629 0.89 RXRA (0.46) RXRARXRBHSD17B10ALDH1A1MAPK1
SCHEMBL6374128 0.89 RXRA (0.46) RXRARXRBHSD17B10ALDH1A1MAPK1
SCHEMBL13903617 0.87 RXRA (0.45) RXRARXRBHSD17B10ALDH1A1MAPK1
SCHEMBL18232204 0.87 RXRA (0.45) RXRARXRBHSD17B10ALDH1A1MAPK1
SCHEMBL13903627 0.87 RXRA (0.45) RXRARXRBHSD17B10ALDH1A1MAPK1
SCHEMBL13903633 0.87 RXRA (0.45) RXRARXRBHSD17B10ALDH1A1MAPK1
SCHEMBL13903618 0.87 RXRA (0.45) RXRARXRBHSD17B10ALDH1A1MAPK1
SCHEMBL24154509 0.85 RXRA (0.44) RXRARXRBHSD17B10ALDH1A1MAPK1
SCHEMBL17811586 0.85 RXRA (0.44) RXRARXRBHSD17B10ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8298684-B2 Phenylcarbazole compounds, organic light emitting device comprising the phenylcarbazole compounds and flat panel display device comprising the organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2012-10-30 US disclosed
US-8298684-B2 Phenylcarbazole compounds, organic light emitting device comprising the phenylcarbazole compounds and flat panel display device comprising the organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2012-10-30 US disclosed
US-8288014-B2 Fluorene-containing compound and organic light emitting device employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-10-16 US disclosed
US-8288014-B2 Fluorene-containing compound and organic light emitting device employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-10-16 US disclosed
US-20100051924-A1 FLUORENE-CONTAINING COMPOUND AND ORGANIC LIGHT EMITTING DEVICE EMPLOYING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-03-04 US disclosed
US-20100051924-A1 FLUORENE-CONTAINING COMPOUND AND ORGANIC LIGHT EMITTING DEVICE EMPLOYING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-03-04 US disclosed
US-20100032656-A1 Phenylcarbazole compounds, organic light emitting device comprising the phenylcarbazole compounds and flat panel display device comprising the organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2010-02-11 US disclosed
US-20100032656-A1 Phenylcarbazole compounds, organic light emitting device comprising the phenylcarbazole compounds and flat panel display device comprising the organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2010-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100051924-A1 FLUORENE-CONTAINING COMPOUND AND ORGANIC LIGHT EMITTING DEVICE EMPLOYING THE SAME SLCO4C1, SLCO2A1, SLCO2B1 RXRA 1419/4885RXRB 2029/4885HSD17B10 3299/4885
US-20100032656-A1 Phenylcarbazole compounds, organic light emitting device comprising the phenylcarbazole compounds and flat panel display device comprising the organic light emitting device OCIAD1, OXA1L, MAP1LC3B RXRA 1038/4885RXRB 722/4885HSD17B10 786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.