Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 18/20 | 0.63 |
| ▸ | PRKAA1 | Q13131 | 18/20 | 0.63 |
| ▸ | PRKAB1 | Q9Y478 | 18/20 | 0.63 |
| ▸ | PRKAB2 | O43741 | 17/20 | 0.63 |
| ▸ | PRKAA2 | P54646 | 17/20 | 0.63 |
| ▸ | PRKAG3 | Q9UGI9 | 17/20 | 0.63 |
| ▸ | PRKAG2 | Q9UGJ0 | 17/20 | 0.63 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603741 | 0.86 | PRKAG1 (0.51) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL11919262 | 0.86 | PRKAG1 (0.51) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL4604740 | 0.83 | PRKAG1 (0.50) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL5430903 | 0.83 | PRKAG1 (0.53) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL27955219 | 0.82 | PRKAG1 (0.48) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL27956765 | 0.82 | KDM4E (0.60) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL28253844 | 0.81 | PRKAG1 (0.47) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL176936 | 0.78 | PRKAG1 (0.55) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL12879075 | 0.78 | PRKAG1 (0.46) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 | |
| SCHEMBL15300913 | 0.78 | PRKAB2 (1.00) | PRKAG1PRKAA1PRKAB1PRKAB2PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |