Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 7/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5952807 | 0.87 | NPC1 (0.46) | NPC1MAPTRAB9ANPBWR1GAA | |
| SCHEMBL13375197 | 0.81 | CBFB (0.47) | CBFBNPC1MAPTRAB9AGAA | |
| SCHEMBL5952630 | 0.81 | AMY1A (0.49) | NPC1MAPTRAB9ANPBWR1GAA | |
| SCHEMBL5952046 | 0.80 | NPBWR1 (0.46) | NPC1MAPTRAB9ANPBWR1GAA | |
| SCHEMBL5952615 | 0.79 | GAA (0.46) | NPC1MAPTRAB9ANPBWR1GAA | |
| SCHEMBL13375032 | 0.79 | CBFB (0.40) | CBFBNPC1MAPTRAB9ANPBWR1 | |
| SCHEMBL5952684 | 0.77 | NPBWR1 (0.44) | NPC1MAPTRAB9ANPBWR1HTT | |
| SCHEMBL5952633 | 0.77 | GUSB (0.48) | CBFBNPC1MAPTRAB9ANPBWR1 | |
| SCHEMBL13375241 | 0.75 | NPBWR1 (0.37) | CBFBNPC1MAPTRAB9ANPBWR1 | |
| SCHEMBL546457 | 0.75 | AMY1A (0.49) | NPC1MAPTRAB9ANPBWR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |