SCHEMBL133754

SCHEMBL133754

Nc1ccc(C(c2ccccc2)c2ccc(N)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.53
CYP3A4 P08684 3/20 0.50
SLC6A2 P23975 2/20 0.50
SLC6A4 P31645 2/20 0.50
SLC6A3 Q01959 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
TAAR1 Q96RJ0 1/20 0.50
HSD17B10 Q99714 1/20 0.50
DPP4 P27487 2/20 0.46
F2 P00734 1/20 0.46
MAPT P10636 5/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CFTR P13569 1/20 0.44
GOPC Q9HD26 1/20 0.44
MAOA P21397 4/20 0.44
ALDH1A1 P00352 3/20 0.44
CYP2C9 P11712 3/20 0.44
CYP2C19 P33261 3/20 0.44
MAOB P27338 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3688628 1.00 TSHR (0.53) TSHRCYP3A4SLC6A2SLC6A4SLC6A3
SCHEMBL22050356 0.88 MEN1 (0.57) TSHRCYP3A4TDP1TAAR1HSD17B10
SCHEMBL223522 0.88 MEN1 (0.57) TSHRCYP3A4TDP1TAAR1HSD17B10
SCHEMBL22862181 0.87 CYP3A4 (0.71) TSHRCYP3A4TDP1TAAR1HSD17B10
SCHEMBL9767941 0.87 MAOA (0.68) TSHRCYP3A4TDP1MAPTMEN1
SCHEMBL10038666 0.87 SLC6A2 (0.75) TSHRCYP3A4SLC6A2SLC6A4SLC6A3
SCHEMBL2956444 0.85 SLC6A2 (0.63) TSHRSLC6A2SLC6A4SLC6A3TAAR1
SCHEMBL22050359 0.84 MEN1 (0.40) TSHRCYP3A4SLC6A2SLC6A4SLC6A3
SCHEMBL18286653 0.83 TYR (0.50) TSHRCYP3A4SLC6A2SLC6A4SLC6A3
SCHEMBL21380569 0.82 TSHR (0.40) TSHRCYP3A4SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219504-B Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2025-03-14 CN claimed
CN-119330905-A Amphiphilic surfactant containing sulfobetaine group benzoxazine, preparation method thereof and efficient oil displacement flushing fluid 成都欧美克石油科技股份有限公司 2025-01-21 CN claimed
CN-119219504-A Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2024-12-31 CN claimed
CN-117362597-A Low-stress underfill capable of being repaired by heating and preparation method and application thereof 深圳先进电子材料国际创新研究院 2024-01-09 CN claimed
CN-114381095-B High-gas-resistance high-temperature-cooking-resistant transparent resin and preparation method and application thereof 佛山市辉鸿塑胶实业有限公司 2023-04-18 CN claimed
CN-115785623-A Flame-retardant basalt fiber reinforced thermosetting resin composite material and application thereof 四川衡耀复合材料科技有限公司 2023-03-14 CN claimed
CN-114381095-A High-gas-resistance high-temperature-cooking-resistant transparent resin and preparation method and application thereof 佛山市辉鸿塑胶实业有限公司 2022-04-22 CN claimed
CN-112341836-B Weak acid red bisazo dye and preparation method thereof 金华恒利康化工有限公司 2021-09-21 CN claimed
CN-112457744-A Graphene modified anticorrosive paint and preparation method thereof 四川科嘉能源科技有限公司 2021-03-09 CN claimed
CN-112341836-A Weak acid red bisazo dye and preparation method thereof 金华恒利康化工有限公司 2021-02-09 CN claimed
US-4393188-A PRINTED CIRCUITS HITACHI CHEMICAL COMPANY, LTD. (JP) 1983-07-12 US claimed
US-4390596-A POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER RHONE-POULENC INDUSTRIES (FR) 1983-06-28 US claimed
US-4389516-A POLYFUNCTIONAL MALEIMIDE OR CYANATE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-06-21 US claimed
US-4370462-A MODIFIED POLYIMIDES HAVING ACETYLENIC END GROUPS AND AN AROMATIC POLYISOCYANATO COMPOUND OR VARNISHES; POLYMER; SOLUBILITY; VARNISHES; LAMINATION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-01-25 US claimed
US-4330669-A POLYMERS OF CYANATE ESTERS FOR NONCRACKING COATINGS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1982-05-18 US claimed
US-4330658-A POLYFUNCTIONAL CYANATE, POLYAMIDEIMIDE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1982-05-18 US claimed
US-4283522-A BY HEATING WITH A DIAMINE HITACHI CHEMICAL COMPANY, LTD. (JP) 1981-08-11 US claimed
US-4238591-A BIS-MALEIMIDE, SILANEDIOL OR SILOXANE RHONE-POULENC INDUSTRIES (FR) 1980-12-09 US claimed
US-4225498-A Preparation of N-substituted oligo-imides RHONE-POULENC INDUSTRIES (FR) 1980-09-30 US claimed
US-4110364-A AND BISMALEIIMIDES MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1978-08-29 US claimed