SCHEMBL223522

SCHEMBL223522

Nc1ccc(C(c2ccc(N)cc2)c2ccc(N)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.57
MAPT P10636 2/20 0.57
KMT2A Q03164 2/20 0.57
CYP3A4 P08684 8/20 0.47
TDP1 Q9NUW8 7/20 0.47
ALDH1A1 P00352 6/20 0.47
TP53 P04637 2/20 0.47
MAPK1 P28482 4/20 0.42
ALOX15 P16050 3/20 0.42
HSD17B10 Q99714 2/20 0.42
ACHE P22303 1/20 0.42
CA3 P07451 1/20 0.42
THRB P10828 1/20 0.42
CA6 P23280 1/20 0.42
CASP1 P29466 1/20 0.42
HIF1A Q16665 1/20 0.42
CA14 Q9ULX7 1/20 0.42
TSHR P16473 5/20 0.40
GFER P55789 1/20 0.40
APP P05067 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22050356 1.00 MEN1 (0.57) MEN1MAPTKMT2ACYP3A4TDP1
SCHEMBL22050412 0.91 ALDH1A1 (0.65) MEN1MAPTKMT2ACYP3A4TDP1
SCHEMBL133754 0.88 TSHR (0.53) MEN1MAPTKMT2ACYP3A4TDP1
SCHEMBL13523893 0.88 MAPT (0.44) MEN1MAPTKMT2ACYP3A4TDP1
SCHEMBL3688628 0.88 TSHR (0.53) MEN1MAPTKMT2ACYP3A4TDP1
SCHEMBL17737832 0.86 ACHE (0.68) MEN1MAPTKMT2ACYP3A4TDP1
SCHEMBL17221836 0.86 MAPT (0.46) MEN1MAPTKMT2ACYP3A4TDP1
SCHEMBL8208247 0.86 ACHE (0.68) MEN1MAPTKMT2ACYP3A4TDP1
SCHEMBL5010075 0.86 CYP19A1 (0.56) MEN1MAPTKMT2ATDP1ALDH1A1
SCHEMBL31409227 0.86 MEN1 (0.42) MEN1MAPTKMT2ACYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1953 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011386-A Polyimide material and preparation method thereof 武汉学院 2026-05-12 CN claimed
US-20250353984-A1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF BLUESHIFT MAT INC (US) 2025-11-20 US claimed
US-12404382-B2 Highly branched non-crosslinked aerogel, methods of making, and uses thereof Blueshift Materials, Inc. (US) 2025-09-02 US claimed
CN-118638295-B Preparation method of high-strength antibacterial thermoplastic polyurethane elastomer 兴邦新材料(山东)有限公司 2024-10-15 CN claimed
CN-118638295-A Preparation method of high-strength antibacterial thermoplastic polyurethane elastomer 兴邦新材料(山东)有限公司 2024-09-13 CN claimed
CN-118388825-B Preparation method of heat-resistant modified asphalt waterproof coiled material 北新防水(安徽)有限公司 2024-09-06 CN claimed
CN-118388825-A Preparation method of heat-resistant modified asphalt waterproof coiled material 北新防水(安徽)有限公司 2024-07-26 CN claimed
US-20240150539-A1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF Blueshift Materials, Inc. 2024-05-09 US claimed
CN-117924096-A Method for synthesizing 4, 4'' -triamino triphenylmethane 北京理工大学 2024-04-26 CN claimed
US-11951449-B2 Method for preparing organic-inorganic hybrid microcapsule LG HOUSEHOLD & HEALTH CARE LTD. (KR) 2024-04-09 US claimed
EP-0776933-A1 Polybutene-1 resin composition and a method of accelerating the crystal transformation NEW JAPAN CHEMICAL CO.,LTD. (JP) 1997-06-04 EP claimed
US-5623023-A BLEND OF EPOXY RESINS, POLYEPOXIDES TAIYO INK MANUFACUTURING CO., LTD. (JP) 1997-04-22 US claimed
WO-1993019143-A1 COLORANT-CONTAINING ELECTRORHEOLOGICAL MATERIALS LORD CORPORATION (US) 1993-09-30 WO claimed
EP-0158394-A1 Process for preparing a polymer alloy, molded product, and reaction injection molded product STAMICARBON B.V. (NL) 1985-10-16 EP claimed
US-4390596-A POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER RHONE-POULENC INDUSTRIES (FR) 1983-06-28 US claimed
US-4258123-A UNSATURATED COMPOUND, HALOGENATED TRIAZINE, UNSATURATED KETONE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US claimed
US-4238591-A BIS-MALEIMIDE, SILANEDIOL OR SILOXANE RHONE-POULENC INDUSTRIES (FR) 1980-12-09 US claimed
US-4225498-A Preparation of N-substituted oligo-imides RHONE-POULENC INDUSTRIES (FR) 1980-09-30 US claimed
US-4196274-A REACTING A POLYSISCYANATE OR POLYISOTHIOCYANATE WITH A MALEAMIC ACID BAYER AKTIENGESELLSCHAFT (DE) 1980-04-01 US claimed
US-4036710-A FROM AN ACIDIC BATH CONTAINING A BASIC DI- OR TRI-AMINO-TRIARYLMETHANE DYE AND A SULFOALKYL SULFIDE M & T CHEMICALS INC. (US) 1977-07-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11951449-B2 Method for preparing organic-inorganic hybrid microcapsule INCENP, PHOSPHO1, CHMP4B MEN1 1723/4885MAPT 819/4885KMT2A 3493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.