SCHEMBL133766

SCHEMBL133766

CCCCCCCCCCCCCCCCCCOC[C@H](CO)OC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.63
LPAR1 Q92633 9/20 0.62
LPAR3 Q9UBY5 9/20 0.62
LPAR2 Q9HBW0 4/20 0.62
LPAR6 P43657 3/20 0.62
LPAR4 Q99677 3/20 0.62
LPAR5 Q9H1C0 3/20 0.62
PRKD3 O94806 2/20 0.59
PRKCG P05129 2/20 0.59
PRKCB P05771 2/20 0.59
PRKCA P17252 2/20 0.59
PRKCH P24723 2/20 0.59
PRKCI P41743 2/20 0.59
PRKCE Q02156 2/20 0.59
PRKCQ Q04759 2/20 0.59
PRKCZ Q05513 2/20 0.59
PRKCD Q05655 2/20 0.59
PRKD1 Q15139 2/20 0.59
HTT P42858 2/20 0.52
MEN1 O00255 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6687853 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2LPAR6
SCHEMBL10933257 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2LPAR6
SCHEMBL10949767 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2LPAR6
SCHEMBL2671655 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2LPAR6
SCHEMBL10566104 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2LPAR6
SCHEMBL10959285 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2LPAR6
SCHEMBL10549855 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2LPAR6
SCHEMBL5796672 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2LPAR6
SCHEMBL10204069 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2LPAR6
SCHEMBL10565936 1.00 USP2 (0.63) USP2LPAR1LPAR3LPAR2LPAR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100086583-A1 LIPID-ANALOGOUS PHOSPHORIC TRIESTERS MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2010-04-08 US claimed
US-7592469-B2 Lipid-analogous phosphoric acid triesters MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2009-09-22 US claimed
EP-1556391-B1 LIPID-ANALOG PHOSPHORIC ACID TRIESTER MAX PLANCK GESELLSCHAFT (DE) 2007-08-01 EP claimed
US-20060039963-A1 Lipid-analogo phosphoric acid triesters MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) 2006-02-23 US claimed
US-20230295201-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2023-09-21 US disclosed
US-20230295201-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2023-09-21 US disclosed
CN-112521518-B Modified starch and preparation method and application thereof 瑞辰星生物技术(广州)有限公司 2023-04-07 CN disclosed
CN-112520831-B Method for recovering free starch in papermaking white water 瑞辰星生物技术(广州)有限公司 2023-03-14 CN disclosed
CN-110476063-B Hydrophilized colored cellulose fine particles 旭化成株式会社 2022-11-15 CN disclosed
CN-115175735-A Antiviral compounds 吉利德科学公司 2022-10-11 CN disclosed
CN-112522989-B Method for making paper 瑞辰星生物技术(广州)有限公司 2022-07-29 CN disclosed
US-10071110-B2 Phosphonate compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-09-11 US disclosed
US-5057530-A For inhibiting blood platelet activating faactors HOFFMANN-LA ROCHE INC. (US) 1991-10-15 US disclosed
US-4863941-A PLATELET ACTIVATING FACTOR INHIBITORS, ANTITUMOR AGENTS HOFFMANN-LA ROCHE INC. (US) 1989-09-05 US disclosed
US-4804789-A D-mannite derivatives as starting products for the synthesis of phospholipids MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 1989-02-14 US disclosed
EP-0147768-B1 GLYCERIN DERIVATIVES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1989-02-08 EP disclosed
US-4739095-A Derivatives of N,N-(2-chloro-ethyl)-phosphoric acid amide MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 1988-04-19 US disclosed
US-4734225-A ANTITUMOR AGENTS MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 1988-03-29 US disclosed
US-4731373-A BLOOD PLATELET ACTIVATING FACTOR HOFFMAN-LA ROCHE INC. (US) 1988-03-15 US disclosed
EP-0208932-A2 Glycerin derivatives F. HOFFMANN-LA ROCHE AG (CH) 1987-01-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295201-A1 ANTIVIRAL COMPOUNDS MAVS, HAVCR2, ZC3HAV1 USP2 4095/4885LPAR1 1068/4885LPAR3 1521/4885
US-10071110-B2 Phosphonate compounds PHPT1, PHOSPHO1, PIK3CA USP2 4514/4885LPAR1 1088/4885LPAR3 1074/4885
US-20060039963-A1 Lipid-analogo phosphoric acid triesters PHOSPHO1, LIPC, LIPA USP2 3905/4885LPAR1 22/4885LPAR3 45/4885
US-20100086583-A1 LIPID-ANALOGOUS PHOSPHORIC TRIESTERS PHOSPHO1, LIPC, LIPA USP2 2903/4885LPAR1 41/4885LPAR3 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.