Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13376585 | 0.91 | IKBKB (0.37) | BRD4GRM5 | |
| SCHEMBL12342077 | 0.90 | BRD4 (0.31) | BRD4 | |
| SCHEMBL2767060 | 0.89 | BRD4 (0.32) | BRD4 | |
| SCHEMBL12341871 | 0.89 | GRM4 (0.32) | BRD4GRM5 | |
| SCHEMBL2768127 | 0.88 | GABRA1 (0.33) | BRD4 | |
| SCHEMBL2766929 | 0.88 | BRD4 (0.31) | BRD4 | |
| SCHEMBL12341875 | 0.87 | BRD4 (0.30) | BRD4 | |
| SCHEMBL2766243 | 0.86 | PTGES (0.36) | BRD4 | |
| SCHEMBL2766241 | 0.84 | CHUK (0.34) | — | |
| SCHEMBL2767712 | 0.84 | IKBKB (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888584-B1 | 1, 6 -DIHYDRO- 1,3, 5, 6-TETRAAZA-AS-INDACENE BASED TRICYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME AS INHIBITORS OF IKK ENZYME ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2010-04-21 | — | — | EP | disclosed |