Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | APEX1 | P27695 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13377546 | 0.87 | EPHX2 (0.54) | POLHKDM4ECYP3A4CYP2D6POLB | |
| SCHEMBL14401209 | 0.87 | EPHX2 (0.54) | POLHKDM4ECYP3A4CYP2D6POLB | |
| SCHEMBL14401119 | 0.77 | CYP3A4 (0.56) | POLHKDM4ECYP3A4CYP2D6POLB | |
| SCHEMBL13377545 | 0.77 | CYP3A4 (0.56) | POLHKDM4ECYP3A4CYP2D6POLB | |
| SCHEMBL14384093 | 0.77 | CYP3A4 (0.46) | POLHKDM4ECYP3A4CYP2D6POLB | |
| SCHEMBL21376116 | 0.76 | POLH (0.75) | POLHKDM4ECYP3A4CYP2D6POLB | |
| SCHEMBL14384281 | 0.75 | CYP3A4 (0.55) | POLHKDM4ECYP3A4CYP2D6POLB | |
| SCHEMBL31573981 | 0.74 | CYP3A4 (0.53) | POLHKDM4ECYP3A4CYP2D6POLB | |
| SCHEMBL13393799 | 0.74 | NQO2 (0.66) | KDM4ECYP3A4POLBAPEX1RECQL | |
| SCHEMBL13393806 | 0.74 | KDM4E (0.53) | KDM4ECYP3A4CYP2D6POLBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718658-B1 | FLAVONOID COMPLEXES COMPRISING CYCLODEXTRINS | MERCK PATENT GMBH (DE) | 2010-04-28 | — | — | EP | disclosed |