Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | POLH | Q9Y253 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31573981 | 0.78 | CYP3A4 (0.53) | CYP3A4CYP2D6POLHKDM4EPOLB | |
| SCHEMBL22058789 | 0.76 | POLH (0.58) | CYP2D6POLHKDM4EPOLBAPEX1 | |
| SCHEMBL14383525 | 0.76 | CYP3A4 (0.51) | CYP3A4CYP2D6POLHKDM4EPOLB | |
| SCHEMBL14401129 | 0.76 | CYP3A4 (0.51) | CYP3A4CYP2D6POLHKDM4EPOLB | |
| SCHEMBL13377325 | 0.75 | POLH (0.52) | CYP3A4CYP2D6POLHKDM4EPOLB | |
| SCHEMBL19490598 | 0.75 | POLH (0.70) | CYP3A4CYP2D6POLHKDM4EPOLB | |
| SCHEMBL21376116 | 0.73 | POLH (0.75) | CYP3A4CYP2D6POLHKDM4EPOLB | |
| SCHEMBL28922584 | 0.73 | TUBB4A (0.55) | CYP3A4CYP2D6POLHKDM4EPOLB | |
| SCHEMBL22549001 | 0.73 | POLH (0.74) | CYP3A4CYP2D6POLHKDM4EPOLB | |
| SCHEMBL14384093 | 0.72 | CYP3A4 (0.46) | CYP3A4CYP2D6POLHKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363594-B1 | COSMETIC FORMULATIONS CONTAINING FLAVONOID DERIVATIVES | MERCK PATENT GMBH (DE) | 2007-11-21 | — | — | EP | disclosed |