SCHEMBL1337818

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4794737	0.81	ADORA1 (0.48)	TP53POLBALDH1A1NPSR1MEN1
	SCHEMBL31522871	0.81	ALDH1A1 (0.45)	TP53POLBALDH1A1NPSR1MEN1
	SCHEMBL12602495	0.81	ALDH1A1 (0.47)	TP53POLBALDH1A1NPSR1MEN1
	SCHEMBL4795149	0.80	SLC5A1 (0.44)	TP53ALDH1A1NPSR1MEN1LMNA
	SCHEMBL31523222	0.80	MEN1 (0.47)	TP53POLBALDH1A1NPSR1MEN1
	SCHEMBL16532421	0.80	MAP3K14 (0.49)	TP53POLBALDH1A1NPSR1MEN1
	SCHEMBL1337554	0.80	CNR2 (0.46)	CYP2C9GRIA2MAP3K14UGCG
	SCHEMBL1337553	0.80	CNR2 (0.46)	CYP2C9GRIA2MAP3K14UGCG
	SCHEMBL31522992	0.79	ALDH1A1 (0.46)	TP53POLBALDH1A1NPSR1MEN1
	SCHEMBL31522846	0.78	LMNA (0.43)	TP53POLBALDH1A1NPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.