Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 4/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19153060 | 0.83 | PDK2 (0.40) | PDK2KDM4EALDH1A1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27969289 | 0.80 | PDK2 (0.46) | PDK2LMNASMN1; SMN2ELANE | |
| SCHEMBL13378366 | 0.74 | PDK2 (0.59) | PDK2ALDH1A1SMN1; SMN2PTPRCPTPN1 | |
| SCHEMBL19152742 | 0.74 | SMN1; SMN2 (0.37) | PDK2ALDH1A1SMN1; SMN2PTPN1 | |
| SCHEMBL13378330 | 0.73 | BACE1 (0.37) | KDM4EALDH1A1LMNAMDM2SMN1; SMN2 | |
| SCHEMBL6060609 | 0.72 | APEX1 (0.42) | PDK2KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19153355 | 0.71 | PTPN5 (0.44) | PDK2LMNAALOX5APFEN1 | |
| SCHEMBL19152599 | 0.70 | HDAC4 (0.36) | PDK2KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19153156 | 0.69 | PDK2 (0.43) | PDK2KDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19153194 | 0.68 | KDR (0.36) | PDK2ALDH1A1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036025-A2 | TRANSITION METAL CATALYTIC SYSTEMS AND METHODS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND α- OLEFINS USING THE SAME. | SK ENERGY CO., LTD. (KR) | 2010-04-01 | — | — | WO | disclosed |