Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.62 |
| ▸ | RELA | Q04206 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CHUK | O15111 | 2/20 | 0.50 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13379428 | 0.92 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL13379331 | 0.91 | ALDH1A1 (0.55) | SMN1; SMN2MAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL13606260 | 0.91 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL13606263 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL13379432 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL13379323 | 0.87 | GPR55 (0.55) | SMN1; SMN2MAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL13379446 | 0.87 | ALDH1A1 (0.50) | SMN1; SMN2MAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL13379394 | 0.87 | ALDH1A1 (0.44) | SMN1; SMN2MAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL13379396 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL13379333 | 0.83 | KDM4E (0.44) | SMN1; SMN2MAPTMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2764053-B1 | IRON(II) CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING (US) | 2017-03-15 | — | — | EP | disclosed |
| US-9328205-B2 | Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2016-05-03 | — | — | US | disclosed |
| US-9328205-B2 | Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2016-05-03 | — | — | US | disclosed |
| US-9156948-B2 | Iron(II) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2015-10-13 | — | — | US | disclosed |
| US-9156948-B2 | Iron(II) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2015-10-13 | — | — | US | disclosed |
| US-20140371056-A1 | Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts | DOW COMING CORPORATION (US) | 2014-12-18 | — | — | US | disclosed |
| US-20140371056-A1 | Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts | DOW COMING CORPORATION (US) | 2014-12-18 | — | — | US | disclosed |
| US-20140296467-A1 | Iron(II) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts | DOW CORNING CORPORATION (US) | 2014-10-02 | — | — | US | disclosed |
| US-20140296467-A1 | Iron(II) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts | DOW CORNING CORPORATION (US) | 2014-10-02 | — | — | US | disclosed |
| WO-2013052588-A1 | IRON(II) CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-04-11 | — | — | WO | disclosed |
| WO-2013052585-A2 | IRON(III) CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2013-04-11 | — | — | WO | disclosed |
| US-7705157-B2 | Phenol-heterocyclic ligands, metal complexes, and their uses as catalysts | SYMYX SOLUTIONS, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| US-20100048841-A1 | PHENOL-HETEROCYCLIC LIGANDS, METAL COMPLEXES, AND THEIR USES AS CATALYSTS | SYMYX SOLUTIONS, INC. (US) | 2010-02-25 | — | — | US | disclosed |