Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14306617 | 0.78 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1 | |
| SCHEMBL1744665 | 0.74 | — | — | |
| SCHEMBL15778116 | 0.71 | HSP90AA1 (0.32) | HSP90AA1HSP90AB1 | |
| SCHEMBL9921485 | 0.71 | MEN1 (0.36) | HSP90AA1HSP90AB1 | |
| SCHEMBL28654635 | 0.70 | — | — | |
| SCHEMBL13380739 | 0.69 | FFAR3 (0.33) | — | |
| SCHEMBL11800416 | 0.68 | NQO1 (0.30) | — | |
| SCHEMBL12216285 | 0.67 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1TAS2R38 | |
| SCHEMBL12689283 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL16439738 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156783-B2 | Compounds for treating proliferative disorders | SYNTA PHARMACEUTICALS CORP. (US) | 2015-10-13 | — | — | US | disclosed |
| US-9156783-B2 | Compounds for treating proliferative disorders | SYNTA PHARMACEUTICALS CORP. (US) | 2015-10-13 | — | — | US | disclosed |
| US-20150025042-A1 | Compounds For Treating Proliferative Disorders | SYNTA PHARMACEUTICALS CORP. (US) | 2015-01-22 | — | — | US | disclosed |
| US-20150025042-A1 | Compounds For Treating Proliferative Disorders | SYNTA PHARMACEUTICALS CORP. (US) | 2015-01-22 | — | — | US | disclosed |
| US-20100081635-A1 | COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS | SYNTA PHARMACEUTICALS CORP. | 2010-04-01 | — | — | US | disclosed |
| US-20100081635-A1 | COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS | SYNTA PHARMACEUTICALS CORP. | 2010-04-01 | — | — | US | disclosed |
| WO-2008024303-A2 | COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS | SYNTA PHARMACEUTICALS CORP. (US) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081635-A1 | COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS | HSPB1, HSP90AB1, HSPA1B | HSP90AA1 10/4885HSP90AB1 2/4885TAS2R38 4524/4885 |
| US-20150025042-A1 | Compounds For Treating Proliferative Disorders | HSP90AB1, HSPB1, HSP90AB2P | HSP90AA1 9/4885HSP90AB1 1/4885TAS2R38 4421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.