Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 10/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13380958 | 0.81 | POLB (0.51) | POLBAPOBEC3AAPOBEC3GCTDSP1CHRM5 | |
| SCHEMBL14272693 | 0.81 | POLB (0.51) | POLBAPOBEC3AAPOBEC3GCTDSP1CHRM5 | |
| SCHEMBL10000236 | 0.80 | POLB (0.43) | POLBAPOBEC3AAPOBEC3GCTDSP1CHRM5 | |
| SCHEMBL13381284 | 0.79 | POLB (0.43) | POLBAPOBEC3AAPOBEC3GCTDSP1CHRM5 | |
| SCHEMBL13381222 | 0.79 | POLB (0.47) | POLBAPOBEC3AAPOBEC3GCTDSP1CHRM5 | |
| SCHEMBL509970 | 0.79 | POLB (0.44) | POLBAPOBEC3AAPOBEC3GCTDSP1CHRM5 | |
| SCHEMBL13381357 | 0.77 | POLB (0.45) | POLBAPOBEC3AAPOBEC3GCTDSP1CHRM5 | |
| SCHEMBL5334097 | 0.75 | CHRM5 (0.44) | POLBAPOBEC3AAPOBEC3GCTDSP1CHRM5 | |
| SCHEMBL18963329 | 0.74 | NPC1 (0.42) | POLBAPOBEC3AAPOBEC3GCTDSP1CHRM5 | |
| SCHEMBL13381301 | 0.74 | POLB (0.43) | POLBAPOBEC3AAPOBEC3GCTDSP1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081693-A1 | THIADIAZOLE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-04-01 | — | — | US | disclosed |
| WO-2008032858-A2 | THIADIAZOLE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081693-A1 | THIADIAZOLE COMPOUND AND USE THEREOF | NR2C2, NR4A3, NR0B2 | POLB 4566/4885APOBEC3A 2940/4885APOBEC3G 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.