SCHEMBL10000236

SCHEMBL10000236

OC1COC(c2ccco2)OC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.43
APOBEC3A P31941 2/20 0.43
APOBEC3G Q9HC16 2/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 3/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPT P10636 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
KMT2A Q03164 2/20 0.39
CHRM5 P08912 10/20 0.38
CHRM3 P20309 10/20 0.38
CHRM1 P11229 9/20 0.38
CHRM2 P08172 9/20 0.38
CHRM4 P08173 9/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
RECQL P46063 2/20 0.38
PKM P14618 1/20 0.36
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17818416 0.84 ALDH1A1 (0.41) POLBAPOBEC3AAPOBEC3GCTDSP1ALDH1A1
SCHEMBL13380972 0.80 POLB (0.47) POLBAPOBEC3AAPOBEC3GCTDSP1ALDH1A1
SCHEMBL509970 0.79 POLB (0.44) POLBAPOBEC3AAPOBEC3GCTDSP1ALDH1A1
SCHEMBL13381222 0.76 POLB (0.47) POLBAPOBEC3AAPOBEC3GCTDSP1ALDH1A1
SCHEMBL13381284 0.76 POLB (0.43) POLBAPOBEC3AAPOBEC3GCTDSP1ALDH1A1
SCHEMBL5334097 0.75 CHRM5 (0.44) POLBAPOBEC3AAPOBEC3GCTDSP1ALDH1A1
SCHEMBL13380958 0.73 POLB (0.51) POLBAPOBEC3AAPOBEC3GCTDSP1ALDH1A1
SCHEMBL14272693 0.73 POLB (0.51) POLBAPOBEC3AAPOBEC3GCTDSP1ALDH1A1
SCHEMBL10000234 0.73 POLB (0.58) POLBAPOBEC3AAPOBEC3GCTDSP1ALDH1A1
SCHEMBL13381357 0.73 POLB (0.45) POLBAPOBEC3AAPOBEC3GCTDSP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160168315-A1 MODIFIED OLIGOESTERS AND MANUFACTURE METHODS OF THE OLIGOESTERS ANHIDRIDOS Y DERIVADOS DE COLOMBIA S.A. ANDERCOL (CO) 2016-06-16 US disclosed
US-8148454-B2 Use of glycerol acetals COGNIS IP MANAGEMENT GMBH (DE) 2012-04-03 US disclosed
US-8148454-B2 Use of glycerol acetals COGNIS IP MANAGEMENT GMBH (DE) 2012-04-03 US disclosed
US-20100216926-A1 Use of Glycerol Acetals COGNIS IP MANAGEMENT GMBH (DE) 2010-08-26 US disclosed
US-20100216926-A1 Use of Glycerol Acetals COGNIS IP MANAGEMENT GMBH (DE) 2010-08-26 US disclosed
EP-2050784-B1 Use of glycerol acetals COGNIS IP MAN GMBH (DE) 2010-08-25 EP disclosed
WO-2009049840-A1 USE OF GLYCEROL ACETALS COGNIS IP MANAGEMENT GMBH (DE) 2009-04-23 WO disclosed
US-20080207927-A1 PROCESS FOR THE PRODUCTION OF GLYCEROL ACETALS COGNIS IP MANAGEMENT GMBH (DE) 2008-08-28 US disclosed
US-20080207927-A1 PROCESS FOR THE PRODUCTION OF GLYCEROL ACETALS COGNIS IP MANAGEMENT GMBH (DE) 2008-08-28 US disclosed
EP-1905767-A1 Process for the preparation of glycerineacetals Cognis IP Management GmbH (DE) 2008-04-02 EP disclosed
US-4077982-A HERBICIDES FMC CORPORATION (US) 1978-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207927-A1 PROCESS FOR THE PRODUCTION OF GLYCEROL ACETALS GK, GAPDH, HOGA1 POLB 753/4885APOBEC3A 2783/4885APOBEC3G 3172/4885
US-20160168315-A1 MODIFIED OLIGOESTERS AND MANUFACTURE METHODS OF THE OLIGOESTERS OSTC, OSGEP, PUF60 POLB 1171/4885APOBEC3A 349/4885APOBEC3G 406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.