⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15831471 | 1.00 | — | — | |
| SCHEMBL18700888 | 1.00 | — | — | |
| SCHEMBL22915706 | 1.00 | — | — | |
| SCHEMBL248969 | 1.00 | — | — | |
| SCHEMBL15831470 | 1.00 | — | — | |
| SCHEMBL14621027 | 0.94 | MBTD1 (0.44) | — | |
| SCHEMBL242797 | 0.94 | MBTD1 (0.44) | — | |
| SCHEMBL90804 | 0.94 | MBTD1 (0.44) | — | |
| SCHEMBL8825950 | 0.94 | MBTD1 (0.44) | — | |
| SCHEMBL166482 | 0.94 | MBTD1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200165640-A1 | FRUCTOSE-6-PHOSPHATE ALDOLASE VARIANTS FOR ALDOL CARBOLIGATIONS | SUSTAINABLE MOMENTUM, S.L. (ES) | 2020-05-28 | — | — | US | disclosed |
| US-20200165640-A1 | FRUCTOSE-6-PHOSPHATE ALDOLASE VARIANTS FOR ALDOL CARBOLIGATIONS | SUSTAINABLE MOMENTUM, S.L. (ES) | 2020-05-28 | — | — | US | disclosed |
| CN-110945122-A | Fructose-6-phosphate aldolase variants for aldol condensation carbon linking | 西班牙高等科研理事会 | 2020-03-31 | — | — | CN | disclosed |
| EP-3388518-A1 | FRUCTOSE-6-PHOSPHATE ALDOLASE VARIANTS FOR ALDOL CARBOLIGATIONS | Consejo Superior de Investigaciones Cientificas (CSIC) (ES) | 2018-10-17 | — | — | EP | disclosed |
| US-7692015-B2 | Economical process for preparing (S, S)-2, 8-diazabicyclo[4.3.0]nonane and its enantiomer | LIANYUNGANG JINKANG PHARMACEUTICAL TECHNOLOGY CO. LTD. (CN) | 2010-04-06 | — | — | US | disclosed |