Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13612540 | 1.00 | MBTD1 (0.44) | MBTD1L3MBTL3EPAS1ALDH1A1L3MBTL1 | |
| SCHEMBL242797 | 1.00 | MBTD1 (0.44) | MBTD1L3MBTL3EPAS1ALDH1A1L3MBTL1 | |
| SCHEMBL26722446 | 1.00 | MBTD1 (0.44) | MBTD1L3MBTL3EPAS1ALDH1A1L3MBTL1 | |
| SCHEMBL12699779 | 1.00 | MBTD1 (0.44) | MBTD1L3MBTL3EPAS1ALDH1A1L3MBTL1 | |
| SCHEMBL4189941 | 1.00 | MBTD1 (0.44) | MBTD1L3MBTL3EPAS1ALDH1A1L3MBTL1 | |
| SCHEMBL8825950 | 1.00 | MBTD1 (0.44) | MBTD1L3MBTL3EPAS1ALDH1A1L3MBTL1 | |
| SCHEMBL13447 | 1.00 | MBTD1 (0.44) | MBTD1L3MBTL3EPAS1ALDH1A1L3MBTL1 | |
| SCHEMBL166482 | 1.00 | MBTD1 (0.44) | MBTD1L3MBTL3EPAS1ALDH1A1L3MBTL1 | |
| SCHEMBL14621027 | 1.00 | MBTD1 (0.44) | MBTD1L3MBTL3EPAS1ALDH1A1L3MBTL1 | |
| SCHEMBL937629 | 1.00 | MBTD1 (0.44) | MBTD1L3MBTL3EPAS1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080262233-A1 | SYNTHESIS OF PREFFERED ISOMER FRACTIONS OF N, N-DIETHYLDECAHYDROQUINOLINIUM CATION | CHEVRON U.S.A. INC. | 2008-10-23 | — | — | US | claimed |
| WO-2008048858-A2 | SYNTHESIS OF PREFERRED ISOMER FRACTIONS OF N,N-DIETHYLDECAHYDROQUINOLINIUM CATION | CHEVRON U.S.A. INC. (US) | 2008-04-24 | — | — | WO | claimed |
| EP-0250179-A2 | BCD tricyclic ergoline part-structure analogues | ELI LILLY AND COMPANY (US) | 1987-12-23 | — | — | EP | claimed |
| US-12612371-B2 | Sigma-1 receptor ligands and therapeutic uses thereof | UNIVERSITE DE STRASBOURG (FR) | 2026-04-28 | — | — | US | disclosed |
| US-12351570-B2 | Disubstituted alkyne derivatives | MERCK PATENT GMBH (DE) | 2025-07-08 | — | — | US | disclosed |
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |
| EP-4554569-A1 | AGENT CONTAINING MALONIC ACID OR ITS DERIVATIVES FOR RESTORING METAL HOMEOSTASIS | Oxford Antibiotic Group GmbH (AT) | 2025-05-21 | — | — | EP | disclosed |
| CN-119866217-A | Agent for restoring metal steady state containing malonic acid or derivative thereof | 牛津抗生素(制药)集团股份有限公司 | 2025-04-22 | — | — | CN | disclosed |
| EP-4076456-B1 | SIGMA-1 RECEPTOR LIGANDS AND THERAPEUTIC USES THEREOF | UNIV STRASBOURG (FR) | 2024-05-01 | — | — | EP | disclosed |
| WO-2024013400-A1 | AGENT CONTAINING MALONIC ACID OR ITS DERIVATIVES FOR RESTORING METAL HOMEOSTASIS | OXFORD ANTIBIOTIC GROUP GMBH (AT) | 2024-01-18 | — | — | WO | disclosed |
| EP-4306107-A1 | METAL HOMEOSTASIS RESTORATION AGENT | Oxford Antibiotic Group GmbH (AT) | 2024-01-17 | — | — | EP | disclosed |
| EP-0006540-B1 | N-DICHLOROACETYL-1,2,3,4-TETRAHYDROQUINALDINE, PROCESS FOR OBTAINING IT, ITS USE FOR PREVENTING CROPS FROM BEING DAMAGED BY HERBICIDES AND SELECTIVE HERBICIDAL COMPOSITIONS BASED ON N-DICHLOROACETYL-1,2,3,4-TETRAHYDROQUINALDINE AND HERBICIDAL ACETANILIDES OR THIOLCARBAMATES | BAYER AG (DE) | 1981-10-07 | — | — | EP | disclosed |
| EP-0023305-A1 | Use of N,N'-bis(halogen-acyl)-diaza-cycloalkanes for the protection of cultivated plants against damage by herbicides | BAYER AG (DE) | 1981-02-04 | — | — | EP | disclosed |
| EP-0023308-A1 | N-acyl-piperidone cetals, process for their preparation and their use as antidotes in the protection of crop plants against damage by herbicides | BAYER AG (DE) | 1981-02-04 | — | — | EP | disclosed |
| EP-0023287-A1 | Antidote for the protection of cultivated plants against damage by herbicides | BAYER AG (DE) | 1981-02-04 | — | — | EP | disclosed |
| EP-0006542-A2 | The use of N-dichloroacetyl-1,2,3,4-tetrahydroisoquinolin as antidote for the protection of cultivated plants against damage caused by herbicidally active acetanilides; combinations thus obtained and process for their preparation | BAYER AG (DE) | 1980-01-09 | — | — | EP | disclosed |
| US-3992387-A | PLANT GROWTH REGULATORS, HERBICIDES AND FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
| US-3969367-A | PLANT GROWTH REGULATOR, HERBICIDE, FUNGICIDE | CIBA-GEIGY CORPORATION (US) | 1976-07-13 | — | — | US | disclosed |
| US-3955957-A | Phosphoryl-acylamines for inhibiting plant growth | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
| US-3941579-A | Regulating the growth of plants and controlling weeds with carbonyl-substituted azabicycloalkanes | CIBA-GEIGY CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612371-B2 | Sigma-1 receptor ligands and therapeutic uses thereof | SIGMAR1, OPRL1, OPRM1 | MBTD1 4335/4885L3MBTL3 2381/4885EPAS1 2313/4885 |
| US-12351570-B2 | Disubstituted alkyne derivatives | BRCA1, MYC, PCNA | MBTD1 2598/4885L3MBTL3 846/4885EPAS1 489/4885 |
| US-20080262233-A1 | SYNTHESIS OF PREFFERED ISOMER FRACTIONS OF N, N-DIETHYLDECAHYDROQUINOLINIUM CATION | DDAH1, HCN2, HCN1 | MBTD1 3920/4885L3MBTL3 4192/4885EPAS1 2241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.