Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 1.00 |
| ▸ | SLC22A1 | O15245 | 4/20 | 1.00 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.68 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.56 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.56 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.56 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norlevorphanol SCHEMBL6900806 | 1.00 | SIGMAR1 (1.00) | SIGMAR1SLC22A1GRIN1GRIN2ACYP2D6 | |
| Norlevorphanol SCHEMBL29851122 | 1.00 | SIGMAR1 (1.00) | SIGMAR1SLC22A1GRIN1GRIN2ACYP2D6 | |
| Norlevorphanol SCHEMBL23823 | 1.00 | SIGMAR1 (1.00) | SIGMAR1SLC22A1GRIN1GRIN2ACYP2D6 | |
| Norlevorphanol SCHEMBL23822 | 1.00 | SIGMAR1 (1.00) | SIGMAR1SLC22A1GRIN1GRIN2ACYP2D6 | |
| Norlevorphanol SCHEMBL4759025 | 1.00 | SIGMAR1 (1.00) | SIGMAR1SLC22A1GRIN1GRIN2ACYP2D6 | |
| Norlevorphanol SCHEMBL18920299 | 1.00 | SIGMAR1 (1.00) | SIGMAR1SLC22A1GRIN1GRIN2ACYP2D6 | |
| Norlevorphanol SCHEMBL20584891 | 1.00 | SIGMAR1 (1.00) | SIGMAR1SLC22A1GRIN1GRIN2ACYP2D6 | |
| Norlevorphanol SCHEMBL21095579 | 1.00 | SIGMAR1 (1.00) | SIGMAR1SLC22A1GRIN1GRIN2ACYP2D6 | |
| Norlevorphanol SCHEMBL20808855 | 1.00 | SIGMAR1 (1.00) | SIGMAR1SLC22A1GRIN1GRIN2ACYP2D6 | |
| Norlevorphanol SCHEMBL14743778 | 1.00 | SIGMAR1 (1.00) | SIGMAR1SLC22A1GRIN1GRIN2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691874-B2 | Neuroprotective properties of dextrorotatory morphinans | KIM, Hyoung-Chun (KR) | 2010-04-06 | — | — | US | disclosed |
| US-7691874-B2 | Neuroprotective properties of dextrorotatory morphinans | KIM, Hyoung-Chun (KR) | 2010-04-06 | — | — | US | disclosed |