Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24663000 | 0.78 | KDM4E (0.40) | KDM4EALDH1A1 | |
| SCHEMBL13384253 | 0.74 | NOS3 (0.40) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL31599932 | 0.73 | PIK3CG (0.39) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL25298176 | 0.73 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL12196956 | 0.70 | — | — | |
| SCHEMBL13384213 | 0.69 | KDM4E (0.37) | KDM4EALDH1A1 | |
| SCHEMBL22727827 | 0.69 | PDE2A (0.38) | NOS3NOS1NOS2KDM4EALDH1A1 | |
| SCHEMBL25848618 | 0.69 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL13732596 | 0.68 | PTGS1 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL29800723 | 0.67 | AURKA (0.42) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696210-B2 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2010-04-13 | — | — | US | disclosed |