Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25054992 | 0.73 | ADORA3 (0.36) | — | |
| SCHEMBL25848615 | 0.72 | ADORA3 (0.38) | NOS3NOS1NOS2 | |
| SCHEMBL18748604 | 0.69 | CHEK1 (0.33) | — | |
| SCHEMBL13384253 | 0.69 | NOS3 (0.40) | NOS3NOS1NOS2 | |
| SCHEMBL13384258 | 0.69 | NOS3 (0.32) | NOS3NOS1NOS2 | |
| SCHEMBL13086299 | 0.68 | — | — | |
| SCHEMBL13086443 | 0.68 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL22727827 | 0.68 | PDE2A (0.38) | NOS3NOS1NOS2 | |
| SCHEMBL25848612 | 0.67 | FABP3 (0.32) | — | |
| SCHEMBL25848614 | 0.64 | HAVCR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708369-B2 | Heteroaromatic compounds having activity against RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2023-07-25 | — | — | US | disclosed |
| US-11708369-B2 | Heteroaromatic compounds having activity against RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708369-B2 | Heteroaromatic compounds having activity against RSV | MAVS, ZC3HAV1, SARS1 | NOS3 2970/4885NOS1 3162/4885NOS2 3070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.