Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.34 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL857530 | 0.83 | ALDH1A1 (0.39) | ADORA3ADORA2BALDH1A1NR1H2NR1H3 | |
| SCHEMBL13643059 | 0.83 | NR4A2 (0.47) | ADORA3ADORA2APOLBKDM4EL3MBTL1 | |
| SCHEMBL2780530 | 0.82 | POLB (0.41) | ADORA3ADORA2APOLBMTORADK | |
| SCHEMBL17622 | 0.79 | CXCR2 (0.42) | POLBMTORADKNISCHALDH1A1 | |
| SCHEMBL672597 | 0.78 | NOTUM (0.42) | POLBMTORADKNISCHALDH1A1 | |
| Hydrochloric Acid SCHEMBL8588873 | 0.77 | CXCR2 (0.41) | POLBMTORADKNISCHALDH1A1 | |
| SCHEMBL535052 | 0.77 | PDE5A (0.44) | ADORA3ADORA2AADORA1POLBALDH1A1 | |
| SCHEMBL6596072 | 0.77 | KMT2A (0.40) | POLBMTORADKNISCHALDH1A1 | |
| SCHEMBL30670275 | 0.77 | MTOR (0.38) | ADORA3ADORA2APOLBMTORADK | |
| SCHEMBL2092717 | 0.77 | MTOR (0.38) | POLBMTORADKNISCHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102236259-A | Radiation sensitivity resin composition for display element, interlayer insulation film, protective film and spacer and forming method thereof | JSR CORP | 2011-11-09 | — | — | CN | disclosed |
| US-7696210-B2 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2010-04-13 | — | — | US | disclosed |
| US-7696210-B2 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2010-04-13 | — | — | US | disclosed |