Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2260452 | 0.86 | SMN1; SMN2 (0.42) | GAARAB9ASMN1; SMN2 | |
| SCHEMBL13384523 | 0.81 | MAPT (0.37) | NPC1GAARAB9ASMN1; SMN2 | |
| SCHEMBL13384661 | 0.77 | MAOA (0.34) | — | |
| SCHEMBL12389316 | 0.76 | HTR2B (0.49) | — | |
| SCHEMBL13384464 | 0.76 | CHEK2 (0.33) | — | |
| SCHEMBL13384439 | 0.75 | POLQ (0.32) | — | |
| SCHEMBL13384645 | 0.72 | HSP90AA1 (0.33) | RAB9ASMN1; SMN2 | |
| SCHEMBL12365069 | 0.70 | PDK2 (0.43) | GAASMN1; SMN2 | |
| SCHEMBL12364981 | 0.70 | PDK2 (0.43) | NPC1RAB9A | |
| SCHEMBL12364995 | 0.69 | PDK2 (0.45) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177505-A1 | BICYCLIC ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2010-04-21 | — | — | EP | disclosed |