Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13385439 | 0.81 | — | — | |
| Iodide SCHEMBL11699715 | 0.79 | ALDH1A1 (0.36) | NOS1KDM4A | |
| Iodide SCHEMBL11699721 | 0.79 | ALDH1A1 (0.36) | NOS1KDM4A | |
| SCHEMBL8050690 | 0.73 | — | — | |
| SCHEMBL4095555 | 0.73 | — | — | |
| SCHEMBL10736671 | 0.72 | GRIN2D (0.55) | NOS3NOS1 | |
| SCHEMBL10736672 | 0.72 | GRIN2D (0.55) | NOS3NOS1 | |
| SCHEMBL11767214 | 0.71 | GRIN2D (0.44) | NOS3NOS1 | |
| SCHEMBL14373125 | 0.70 | ALDH1A1 (0.35) | ADRA2AKDM4A | |
| SCHEMBL6928681 | 0.70 | SIGMAR1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700581-B2 | Cephalosporin compounds comprising a C3 thio-methyl moiety substituted with N-containing heterocyclic group, and a C7 thiourea acetamido group, their preparations and uses thereof | GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO., LTD. (CN) | 2010-04-20 | — | — | US | disclosed |
| US-20080182836-A1 | Cephalosporin compounds comprising a C3 thio-methyl moiety substituted with N-containing heterocyclic group, and a C7 thiourea acetamido group, their preparations and uses thereof | GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO., LTD. (CN) | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182836-A1 | Cephalosporin compounds comprising a C3 thio-methyl moiety substituted with N-containing heterocyclic group, and a C7 thiourea acetamido group, their preparations and uses thereof | C5, TPMT, C9 | ADRA2A 3893/4885NOS3 1938/4885NOS1 2975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.